Harald Paganetti is a Professor of Radiation Oncology at Harvard Medical School and Director of Physics Research for the Department of Radiation Oncology at Massachusetts General Hospital. He received his PhD in experimental nuclear physics in 1992 from the Rheinische-Friedrich-Wilhelms University in Bonn, Germany. He has been working in radiation therapy research since 1994 and has made many significant contributions to the field of radiation oncology physics and biology. He has published more than 250 peer-reviewed publications and various book chapters and edited 3 books on proton radiation therapy. His main research interests include all aspects of planning and delivery uncertainties in radiation therapy, including biological effect modeling, Monte Carlo dose calculation, as well as advanced optimization and imaging techniques. His current work specifically focuses on optimizing systemic effect of radiation treatments to increase the biological efficacy of radiation therapy. In addition to his research, he serves on editorial boards and is a member of task-groups and committees for various associations such as the National Council on Radiation Protection and Measurements (NCRP) and the American Society for Therapeutic Radiology and Oncology (ASTRO).