Gustavo Adolfo Gámez, Colombia
Basic and Applied Microbiology (MICROBA) Research Group School of Microbiology, University of Antioquia, UdeAAuthor Of 6 Presentations
A NEW FLEXIBLE-GENOMIC TWO-COMPONENT REGULATORY SYSTEM FOR STREPTOCOCCUS PNEUMONIAE AND THE IMPACT OF PNEUMOCOCCAL VACCINES FROM ANOTHER GENOMIC PERSPECTIVE (ID 399)
POST-VACCINATION EPIDEMIOLOGY OF PNEUMOCOCCAL CARRIAGE AMONG CHILDREN YOUNGER THAN FIVE YEARS OF AGE IN CAPE COAST, GHANA (ID 685)
A NEW CONVENTIONAL-PCR STRATEGY FOR DIFFERENTIAL DETECTION OF S.PNEUMONIAE AND S.PSEUDOPNEUMONIAE FROM NON-STERILE-SOURCES CONFIRMS HIGH LEVELS OF NASOPHARYNGEAL CARRIAGE AMONG HEALTHY OLDER-ADULTS FROM MEDELLÍN, COLOMBIA (ID 398)
- Santiago Cardona, Colombia
- Juliana Andrea Carmona, Colombia
- Laura Leandra Beltrán, Colombia
- Andrés Felipe Castro, Colombia
- María Alejandra Palacio, Colombia
- José Luis Torres, Colombia
- Johan Alexis Bolivar, Colombia
- Leidy Johana Acevedo, Colombia
- Laura Mery Muñoz, Colombia
- Luis Felipe Vélez, Colombia
- Yulieth Alexandra Zúñiga, Colombia
- Anlly Banessa Holguín, Colombia
- Miriam Estela Molina, Colombia
- John Jairo Ruiz, Colombia
- Deissy Vargas, Colombia
- Catalina María Arboleda, Colombia
- Jessica Lorena Morales, Colombia
- Alejandro Gómez, Germany
- Sven Hammerschmidt, Germany
- Gustavo Adolfo Gámez, Colombia
GENOMIC CHARACTERIZATION OF STREPTOCOCCUS PNEUMONIAE SEROTYPE 19A ISOLATES CAUSING INVASIVE PNEUMOCOCCAL DISEASES AMONG CHILDREN AND ELDERLY FROM BOGOTÁ, COLOMBIA (ID 432)
CHARACTERIZATION OF STREPTOCOCCUS PNEUMONIAE SEROTYPE 19A CAUSING INVASIVE PNEUMOCOCCAL DISEASE FROM BOGOTÁ, COLOMBIA (ID 997)
Abstract
Background
Invasive Pneumococcal Disease (IPDs) is a leading cause of morbidity and mortality. In Colombia, the 7-valent pneumococcal conjugate vaccine was introduced in 2006 and replaced in 2011 by 10-valent. However, the number of S.pneumoniae serotype-19A causing IPDs in Bogotá has considerably increased in the last years. Thus, we characterized all S.pneumoniae serotype-19A isolates received from the Public Health Laboratory Network of Bogotá (PHLNB) in 2017, after Pneumococcal Conjugate Vaccine implementation.
Methods
This study was conducted with all S.pneumoniae serotype-19A isolates received in 2017 from PHLNB. Standard laboratory methods were performed for pneumococcal culture. Identification and antimicrobial susceptibility/resistance were done by automated method (VITEK-BioMérieux). Serotyping results (Quellung Reaction) were received by feedback of the Colombian National Institute of Health. Statistical analysis: Excel/SPSS.
Results
In 2017, 227 S.pneumoniae IPD-isolates were received from PHLNB. The most prevalent serotypes were 19A/3/23A/9N/6C/14/35B. Serotype-19A accounted for 20.3% (46/227) of IPD-isolates. Twenty-two (47.8%) children <5 years were affected by this serotype in 2017 with Pneumonia (39.1%) and Sepsis (34.9%). All 46 serotype-19A were susceptible to vancomycin and chloramphenicol, while reduced susceptibility and/or resistance was observed for erythromycin (100%), penicillin (65.2%) and Trimetoprim-Sulfametoxazol (58.7%).
Conclusions
These results evidence the predominant emergency of S.pneumoniae multidrug-resistant serotype-19A, among children <5 years in Bogotá-Colombia.
ASSOCIATED FACTORS AND NASOPHARYNGEAL CARRIAGE OF STREPTOCOCCUS PNEUMONIAE AMONG HEALTHY CHILDREN ATTENDING AN OUTPATIENT CLINIC IN THE SOUTH-WESTERN OF COLOMBIA (ID 394)
- Jessica Lorena Morales, Colombia
- Juan Pablo Rojas, Colombia
- Santiago Cardona, Colombia
- Juan David Castillo, Colombia
- María Alejandra Palacio, Colombia
- Luis Fernando Mejía, Colombia
- José Luis Torres, Colombia
- Jaime Contreras, Colombia
- Laura Mery Muñoz, Colombia
- Javier Criales, Colombia
- Luis Felipe Vélez, Colombia
- Angélica María Forero, Colombia
- Yulieth Alexandra Zúñiga, Colombia
- María Eugenia Cuastumal, Colombia
- Leidy Johana Acevedo, Colombia
- Álvaro Jesús Molina, Colombia
- Johan Alexis Bolivar, Colombia
- Alejandro Gómez, Germany
- Sven Hammerschmidt, Germany
- Gustavo Adolfo Gámez, Colombia