Gustavo Adolfo Gámez, Colombia

Basic and Applied Microbiology (MICROBA) Research Group School of Microbiology, University of Antioquia, UdeA

Author Of 6 Presentations

 Conference Calendar

POST-VACCINATION EPIDEMIOLOGY OF PNEUMOCOCCAL CARRIAGE AMONG CHILDREN YOUNGER THAN FIVE YEARS OF AGE IN CAPE COAST, GHANA (ID 685)

Session Name
Vaccines - Impact of Vaccine programs and Serotype Replacement
Presenter
Authors

A NEW CONVENTIONAL-PCR STRATEGY FOR DIFFERENTIAL DETECTION OF S.PNEUMONIAE AND S.PSEUDOPNEUMONIAE FROM NON-STERILE-SOURCES CONFIRMS HIGH LEVELS OF NASOPHARYNGEAL CARRIAGE AMONG HEALTHY OLDER-ADULTS FROM MEDELLÍN, COLOMBIA (ID 398)

Session Name
Clinical Sciences - Diagnosis
Presenter
Authors

GENOMIC CHARACTERIZATION OF STREPTOCOCCUS PNEUMONIAE SEROTYPE 19A ISOLATES CAUSING INVASIVE PNEUMOCOCCAL DISEASES AMONG CHILDREN AND ELDERLY FROM BOGOTÁ, COLOMBIA (ID 432)

Session Name
Basic Sciences - Genomics and Transmission
Presenter
Authors

CHARACTERIZATION OF STREPTOCOCCUS PNEUMONIAE SEROTYPE 19A CAUSING INVASIVE PNEUMOCOCCAL DISEASE FROM BOGOTÁ, COLOMBIA (ID 997)

Session Name
Basic Sciences - Conventional and Molecular Microbiology
Presenter
Authors

Abstract

Background

Invasive Pneumococcal Disease (IPDs) is a leading cause of morbidity and mortality. In Colombia, the 7-valent pneumococcal conjugate vaccine was introduced in 2006 and replaced in 2011 by 10-valent. However, the number of S.pneumoniae serotype-19A causing IPDs in Bogotá has considerably increased in the last years. Thus, we characterized all S.pneumoniae serotype-19A isolates received from the Public Health Laboratory Network of Bogotá (PHLNB) in 2017, after Pneumococcal Conjugate Vaccine implementation.

Methods

This study was conducted with all S.pneumoniae serotype-19A isolates received in 2017 from PHLNB. Standard laboratory methods were performed for pneumococcal culture. Identification and antimicrobial susceptibility/resistance were done by automated method (VITEK-BioMérieux). Serotyping results (Quellung Reaction) were received by feedback of the Colombian National Institute of Health. Statistical analysis: Excel/SPSS.

Results

In 2017, 227 S.pneumoniae IPD-isolates were received from PHLNB. The most prevalent serotypes were 19A/3/23A/9N/6C/14/35B. Serotype-19A accounted for 20.3% (46/227) of IPD-isolates. Twenty-two (47.8%) children <5 years were affected by this serotype in 2017 with Pneumonia (39.1%) and Sepsis (34.9%). All 46 serotype-19A were susceptible to vancomycin and chloramphenicol, while reduced susceptibility and/or resistance was observed for erythromycin (100%), penicillin (65.2%) and Trimetoprim-Sulfametoxazol (58.7%).

Conclusions

These results evidence the predominant emergency of S.pneumoniae multidrug-resistant serotype-19A, among children <5 years in Bogotá-Colombia.

Hide

ASSOCIATED FACTORS AND NASOPHARYNGEAL CARRIAGE OF STREPTOCOCCUS PNEUMONIAE AMONG HEALTHY CHILDREN ATTENDING AN OUTPATIENT CLINIC IN THE SOUTH-WESTERN OF COLOMBIA (ID 394)

Session Name
Population Sciences - Epidemiology, Economics, and Mathematical Modelling
Presenter
Authors

A NEW FLEXIBLE-GENOMIC TWO-COMPONENT REGULATORY SYSTEM FOR STREPTOCOCCUS PNEUMONIAE AND THE IMPACT OF PNEUMOCOCCAL VACCINES FROM ANOTHER GENOMIC PERSPECTIVE (ID 399)

Session Name
Clinical Sciences - Diagnosis
Presenter
Authors