University Hospital Southampton
NIHR Southampton Clinical Research Facility
Professor Edwards is a Consultant Rheumatologist and Co-Director of the NIHR Southampton Clinical Research Facility within the University Hospital Southampton NHS Foundation Trust, having previously worked as a consultant at Tan Tock Seng Hospital in Singapore. Professor Edwards trained with Professor Maini at the Kennedy Institute of Rheumatology during the early years of anti-TNF trials and with Professor Graham Hughes at the St Thomas’ Hospital Lupus Clinic in London. He has been an Investigator on a number of trials of therapies for inflammatory rheumatic diseases. As Co-Director of the NIHR Southampton Clinical Research Facility he is engaged with the running of a large translational research facility with phase I experience including COVID vaccines and anti-virals. Professor Edwards is Clinical Director of the Southampton Musculoskeletal Research Unit, a recognised EULAR centre of excellence and is Chair of the EULAR Education Committee. Professor Edwards is an investigator for a number of stratified medicine trials to better understand the targeting of therapies for individuals.

Moderator of 2 Sessions

Date
Sun, 12.06.2022
Session Time
08:00 - 10:00
Room
ALEXANDRA TRIANTI
Session Type
PLENARY SESSIONS
Date
Mon, 13.06.2022
Session Time
10:30 - 12:30
Room
ALEXANDRA TRIANTI
Session Type
PARALLEL SESSIONS

Presenter of 1 Presentation

IS039 - RA AND THE BRAIN (ID 903)

Date
Mon, 13.06.2022
Session Time
08:00 - 10:00
Session Type
PLENARY SESSIONS
Room
ALEXANDRA TRIANTI
Lecture Time
08:30 - 09:00

Abstract

Abstract Body

Rheumatoid arthritis (RA) was initially described as an inflammatory and destructive disease of synovial joints. However, over the last 20 years increasing focus has been directed towards the effects of chronic systemic inflammation on other organ systems. It is now clear that inflammation plays an important negative role in the development of cardiovascular disease and that DMARDs can reduce this risk. More recent research has considered the increased risk of brain related pathology such as stroke along with pain, depression/anxiety and even cognitive function. It has also been suggested that RA provides a model system to explore the consequences of chronic inflammation of relevance to all populations. This may be true for cardiovascular disease and dementia.

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