Author Of 2 Presentations
P1049 - "Quality of life in multiple sclerosis. Beyond disability: Resilience, fatigue, anxiety and depression as determinants" (ID 1374)
Abstract
Background
Previous studies suggest that fatigue, depression, anxiety and disability affect quality of life in Multiple sclerosis. Resilience has emerged as a modulator of quality of life. There are few studies exploring the relationship between quality of life and resilience in Multiple Sclerosis patients in the context of recognized determinants as fatigue, neuropsychiatric symptoms and disability.
Objectives
To evaluate relationship between quality of life and resilience, disability, fatigue, anxiety and depression in patients with Multiple Sclerosis.
Methods
52 Multiple Sclerosis patients were evaluated with the Functional Assessment Multiple Sclerosis for quality of life, Connor-Davidson 25 Resilience Scale, Modified Fatigue Impact Scale, Hospital Anxiety and Depression Scale, Functional Independence Measure, Symbol digit modalities test and Expanded Disability Status Scale.
Results
Patients with higher scores of resilience and functional independence had higher Quality of life scores. Patients with higher fatigue, anxiety and depression had lower quality of life scores. Expanded Disability Status Scale and duration of the disease were unrelated to quality of life.
Conclusions
Resilience, functional independence, fatigue, anxiety and depression are independently related and determine the variability of quality of life. Look beyond disability is important for the improvement of Quality of life in patients with Multiple Sclerosis.
P1053 - "Resilience in multiple sclerosis relationship with disability, fatigue, anxiety, depression and cognition" (ID 1346)
Abstract
Background
Resilience is a construct defined as the capability of positive adaptation despite adversity. In the context of wellness research in Multiple Sclerosis (MS), resilience has been cited as one of the factors that may mediate emotional wellness. In patients with MS there are few studies on resilience and factors correlated with it.
Objectives
To evaluate resilience in MS patients and its relationship with disability, fatigue, anxiety, depression and cognition.
Methods
52 Multiple Sclerosis patients were evaluated in a longitudinal study using Connor-Davidson 25 Resilience Scale, Modified Fatigue Impact Scale, Hospital Anxiety and Depression Scale, Functional Independence Measure (FIM), Symbol digit modalities test (SDMT) for cognition and Expanded Disability Status Scale (EDSS).
Results
EDSS score (rs= -0.29; p= 0.041), fatigue (r= -0,35; p= 0,012), anxiety (rs= -0.41; p<0.05) and depression (rs= -0.52; p<0.001) were negatively correlated to resilience. Cognition evaluated by SDMT (r= 0,35; p=0,011) and Independence measured by FIM (r= 0.37; p<0.01) were positively correlated to resilience. In multiple regression analyses, depression and cognition were retained as independently factors related to resilience.
Conclusions
Resilience in MS patients could be determined by depression and cognitive status. Seeing beyond physical disability and targeting depression is a possible way to improve resilience and consequently emotional wellness and quality of life in MS patients.