Previous studies suggest that fatigue, depression, anxiety and disability affect quality of life in Multiple sclerosis. Resilience has emerged as a modulator of quality of life. There are few studies exploring the relationship between quality of life and resilience in Multiple Sclerosis patients in the context of recognized determinants as fatigue, neuropsychiatric symptoms and disability.
To evaluate relationship between quality of life and resilience, disability, fatigue, anxiety and depression in patients with Multiple Sclerosis.
52 Multiple Sclerosis patients were evaluated with the Functional Assessment Multiple Sclerosis for quality of life, Connor-Davidson 25 Resilience Scale, Modified Fatigue Impact Scale, Hospital Anxiety and Depression Scale, Functional Independence Measure, Symbol digit modalities test and Expanded Disability Status Scale.
Patients with higher scores of resilience and functional independence had higher Quality of life scores. Patients with higher fatigue, anxiety and depression had lower quality of life scores. Expanded Disability Status Scale and duration of the disease were unrelated to quality of life.
Resilience, functional independence, fatigue, anxiety and depression are independently related and determine the variability of quality of life. Look beyond disability is important for the improvement of Quality of life in patients with Multiple Sclerosis.