Miren Taberna (Spain)

Institut català d'Oncologia Medical Oncology Department

Presenter of 2 Presentations

 Conference Calendar
Workshop 2: Screening and Management in Non-cervical Disease Hall C

Diagnosing and management of HPV-associated oropharyngeal cancer (ID 32)

Session Date
07/20/2020
Session Time
11:00 - 12:25
Room
Hall C
Session Type
Clinical Science
Session Name
Workshop 2: Screening and Management in Non-cervical Disease
Lecture Time
11:43 - 12:03
Presenter
Authors
Clinical Research / Diagnosis and Management of Oropharyngeal, Head and Neck Cancer ePoster

ETIOLOGICAL FACTORS IN OROPHARYNX AND ORAL CAVITY SQUAMOUS CELL CARCINOMA DIAGNOSED AT YOUNG AGE: A SPANISH COHORT AND AN USA CASE-CONTROL STUDY. (ID 1271)

Session Date
07/21/2020
Session Time
10:00 - 17:00
Room
ePoster
Session Type
Poster Viewing - 20-24 July
Session Name
Clinical Research / Diagnosis and Management of Oropharyngeal, Head and Neck Cancer
Lecture Time
10:03 - 10:04
Presenter
Authors

Abstract

Introduction

There is a gap in knowledge in the etiological factors in head and neck cancers diagnosed at young age. The aim of this study is to compare the demographic, toxic habits and HPV status between a Spanish retrospective cohort of oropharyngeal cancer (OPC) patients (≤45 years old vs >45 years). Furthermore, we have analyzed the toxic habits status between young cases and controls from an USA case-control study (including OPC and oral cavity cancers-OC).

Methods

We have reanalyzed data from a retrospective cohort of patients diagnosed with OPC in four Catalonian hospitals from 1990 to 2017 and a case-control study in USA from 2011 to 2014 at The Ohio State University Medical Center. In the OPC cohort unconditional logistic regression was used to compare age groups. Differences in characteristics between cases and controls were compared using the Pearson’s Chi2 test.

Results

49 young and 816 old OPC patients were included from the Spanish cohort and 23 young cases and 46 controls from the USA study. Spanish cohort characteristics comparing young and old OPC patients are described in Table 1. No significant differences were reported in gender, toxic habits or HPV status (positivity: 12.2% vs 7.5% in young and old OPC patients, respectively). There were more non-smokers HPV-related OPC patients than HPV-negative ones (p-value<0.001) in both age groups. A descriptive of the toxic habits of the patients with OC stratified by case or control in the USA study is describe in table 2. There were no statistically significant differences between cases and controls for all toxic habits evaluated; 57.8% of cases (24) were HPV-positive.

tabla 1.jpgtabla 2.jpg

Conclusions

No significant differences were reported in gender, toxic habits or HPV status between young and old OPC patients; neither between young cases and controls regarding tobacco, alcohol or marijuana use.

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Moderator of 1 Session

 Conference Calendar
Clinical Science Oral Session

00820 - Oral Session 7: Oropharyngeal Cancer - Biomarkers for Diagnosis and Prognosis (ID 78)

Session Type
Clinical Science Oral Session
Session Date
07/23/2020
Session Time
07:30 - 08:10
Room
Hall C
Chair(s)

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