N. Shabshin (Ra'anana, IL)

Hospital of University of Pennsylvania Diagnostic Imaging
Nogah Shabshin; MD; MBA; BSC is a musculoskeletal radiologist. She is staff and adjunct professor of Radiology at the hospital of the University of Pennsylvania; Philadlephia since 2008; and leading the MSK radiology at the Emek medical center; Afula; Israel. She is a member of the editorial board of Skeletal Radiology since 2008; chair of the promotion committee of the refresher course of the International Skeletal Society since 2014 and a member of the additional committees in the organization. She received the Fellow research award by (2001); cum laude educational exhibits (2009) from the Radiological Society of North America and an honorarium (2005). She is an author and co-author of 49 scientific papers and 3 chapters and well as 92 scientific presentations and more than 33 invited lectures. She graduated (Cum Laude) the Rapaport School of medicine at the Technion; Haifa and received a Kellog-Rcanati MBA degree (2011). She completed her Radiology residency at Soroka University Medical Center; Beer-Sheba; Israel and a Musculoskeletal radiology fellowship at Thomas Jefferson Medical College; Philadelphia; PA. She was an assistant professor of Radiology at Drexel University; Philadelphia; PA. She founded the Musculoskeletal radiology section at Sheba Medical Center. Dr. Shabshin Completed her MBA studies at Kellogg-Recanati business school. She then served as chair of Radiology at Assuta University Medical Center Network and (2011-2014) and as interim chair of Radiology at Carmel Medical Center. She currently shares her time between clinical-academic work and medical start-up companies. Areas of interest: Bone marrow edema syndromes; stress fractures; musculoskeletal injuries in pregnancy; osteoid osteoma ablations and deep tissue injuries.

Presenter Of 1 Presentation

Podium Presentation Meniscus

10.3.11 - Two-Year MRI Follow-Up on Medial Compartment Cartilage: Superiority of Implanted Synthetic Medial Meniscus Over Non-Surgical Care

Presentation Topic
Meniscus
Date
13.04.2022
Lecture Time
13:00 - 13:00
Room
Bellevue
Session Type
Free Papers
Disclosure
Nogah Shabshin, Active Implants, Consultancy Kenneth Zaslav, Active Implants, Consultancy Christian Lattermann, Active Implants, Consultancy Christopher Kaeding, Active Implants, Consultancy

Abstract

Purpose

This study aims to compare the medial compartment cartilage condition in patients implanted with a NUsurface to non-surgical controls, on a 2-year follow-up MRI.

Methods and Materials

Population: 242 subjects with a history of partial meniscectomy of at least 6 months, suffering from knee pain (176 NUsurface implanted, 66 non-surgical care). Methods: A randomized controlled superiority trial compared the medial compartment cartilage condition in NUsurface patients and controls on a 2-year follow-up MRI. Evaluation of the cartilage was obtained using a Outerbridge method1. Cartilage lesions were classified to full-thickness and non-full-thickness lesions (partial thickness defects or no morphological cartilage defects). Statistical analysis was conducted using Fisher’s exact test.

Results

At 2-year follow-up 17/116 (14.7%) NUsurface patients and 14/32 (43.8%) controls deteriorated from non-full thickness to full-thickness lesions in the medial compartment (P=0.001). At baseline, both groups presented similar proportions of full-thickness cartilage defects in the medial femoral condyle (MFC) (26.6% vs 25.6%) (p>0.05) and at 2-years follow-up full-thickness defects were seen in 33/158 (20.9%) of implanted patients vs 24/43 (55.8%) in controls. After 2-years, improvement in the MFC cartilage was significantly higher in implanted patients vs controls (26/42 (61.9%):1/11 (9.1%), respectively (p=0.002)). There was no significant difference in the MTP results.

Conclusion

Two-year results from the FDA-regulated clinical trial demonstrate that the NUsurface implant provides superior protection of the medial compartment cartilage, specifically the MFC, in post meniscectomy patients, when compared to non-surgical care. By reducing or slowing cartilage deterioration, utilizing a replaceable synthetic meniscus, total knee arthroplasty may be delayed.

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