A. Gobbi (Milano, IT)

Orthopaedic Arthroscopic Surgery International Sport and Medicine

Presenter Of 6 Presentations

Podium Presentation Others

Opening Ceremony

Presentation Topic
Others
Lecture Time
16:15 - 16:35
Session Type
Plenary Session
Corresponding Author
Podium Presentation Others

General assembly

Presentation Topic
Others
Lecture Time
17:30 - 18:30
Session Type
General Assembly
Corresponding Author
Extended Abstract (for invited Faculty only) Extracellular Matrix

9.5.1 - Adipose Tissue Vs. Cellular Matrix

Presentation Number
9.5.1
Presentation Topic
Extracellular Matrix
Lecture Time
12:45 - 13:00
Session Type
Industry Satellite Symposium
Corresponding Author
Extended Abstract (for invited Faculty only) Joint Specific Cartilage Repair

13.3.5 - Case Presentation 5

Presentation Number
13.3.5
Presentation Topic
Joint Specific Cartilage Repair
Lecture Time
08:10 - 08:20
Session Type
Instructional Course
Corresponding Author
Podium Presentation Cartilage /Cell Transplantation

18.1.9 - Long-term Clinical Outcomes of Cartilage Repair in the Knee Using Hyaluronic Acid-based Scaffold with Bone Marrow Aspirate Concentrate.

Presentation Number
18.1.9
Presentation Topic
Cartilage /Cell Transplantation
Lecture Time
15:27 - 15:36
Session Type
Free Papers
Corresponding Author

Abstract

Purpose

To investigate the long-term clinical outcomes of cartilage repair in the knee using a hyaluronic acid-based scaffold seeded with bone marrow aspirate concentrate (HA-BMAC) for the treatment of full-thickness cartilage injury.

Methods and Materials

Patients treated for full-thickness chondral defects in the knee with HA-BMAC were prospectively followed for a mean duration of 10 years (range 6-12 years). Clinical outcomes were examined using patient reported scoring instruments that consisted of the Tegner Activity Scale, the International Knee Documentation Committee (IKDC) Subjective score, the visual analogue scale (VAS), and the Knee Injury and Osteoarthritis Outcome Score (KOOS). Comparative analysis of preoperative and postoperative scores was performed and the effects of patient age, BMI, lesion size, number of treated lesions, and concurrent treatment with associated procedures were examined.

Results

Twenty-seven patients (mean age 48 years) were prospectively evaluated for a mean duration of 10 years (range 6-12 years). All scores were significantly increased at final follow-up (p<0.001). No difference in mean outcome scores were identified after categorization of patients by age, lesion size, treatment of multiple lesions, treatment of multiple knee compartments, and treatment of associated procedures. Rank correlation analysis demonstrated a negative correlation of patient age and final outcome scores of IKDC, Tegner, VAS, and KOOS subsets of Pain, ADL, Sports, and QOL. No association of BMI or lesion size and outcome scores was identified.

Conclusion

Repair of full-thickness cartilage injury in the knee using a hyaluronic acid-based scaffold with activated bone marrow aspirate concentrate provides good to excellent clinical outcomes in large lesions at long-term follow-up. Good clinical outcomes can be expected in patients over 45 years of age, but outcomes may be comparatively more successful in younger patients.

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Extended Abstract (for invited Faculty only) Clinical Outcome

22.0.12 - Surgery Provides Better Outcomes

Presentation Number
22.0.12
Presentation Topic
Clinical Outcome
Lecture Time
09:55 - 10:00
Session Type
Plenary Session
Corresponding Author

Moderator Of 6 Sessions

Lord Byron - ICRS Meeting Room (20) ICRS Committee Meeting

Executive Board (Actual Board)

Session Type
ICRS Committee Meeting
Date
05.10.2019
Time
08:45 - 10:00
Location
Lord Byron - ICRS Meeting Room (20)
Regency Plenary Session
Plaza B&C Industry Satellite Symposium
Session Type
Industry Satellite Symposium
Date
06.10.2019
Time
12:30 - 13:00
Location
Plaza B&C
Regency Free Papers
Session Type
Free Papers
Date
07.10.2019
Time
14:15 - 15:45
Location
Regency

Meeting Participant of

Lord Byron - ICRS Meeting Room (20) ICRS Committee Meeting

Cartilage GmbH Meeting

Session Type
ICRS Committee Meeting
Date
06.10.2019
Time
08:00 - 08:15
Location
Lord Byron - ICRS Meeting Room (20)
Lord Byron - ICRS Meeting Room (20) ICRS Committee Meeting

Finance Committee

Session Type
ICRS Committee Meeting
Date
05.10.2019
Time
12:15 - 13:00
Location
Lord Byron - ICRS Meeting Room (20)
Lord Byron - ICRS Meeting Room (20) ICRS Committee Meeting

Executive Board (Actual Board)

Session Type
ICRS Committee Meeting
Date
05.10.2019
Time
08:45 - 10:00
Location
Lord Byron - ICRS Meeting Room (20)
Lord Byron - ICRS Meeting Room (20) ICRS Committee Meeting

ICRS Diamond Partners

Session Type
ICRS Committee Meeting
Date
07.10.2019
Time
11:00 - 12:00
Location
Lord Byron - ICRS Meeting Room (20)