Author Of 2 Presentations
C-REACTIVE PROTEIN EVALUATION IN DIAGNOSIS OF NEONATAL SEPSIS
Abstract
Background
Background: C - reactive protein (CRP) detection is a nonspecific response to neonatal sepsis, but along with clinical symptoms is helpful, it is an early inflammatory marker, and readily available, less costly makes it an easy test to screen for neonatal sepsis especially in developing countries.
Objectives
Objective: The purpose of this study is to evaluate the early detection of CRP and its correlation to blood culture to diagnose neonatal sepsis.
Methods
Methods: The study was conducted in the special care baby unit at the University Hospital of Tripoli (Tripoli Medical Centre) on the period (January 2013 –December2014). Data of 100 neonates under clinical diagnosis of sepsis were reviewed retrospectively. .Blood culture was sent for all neonates, CRP was done quantitatively by rapid latex agglutination method and cut off value of CRP was taken as 6mg/l. Data analysis was carried out by SPSS version 25 and a p-value < 0.05 considered as statistically significant.
Results
Out of 100 patients studied 70% were above 2.500 g, 72% were normal vaginal delivery and 45% presented with fever. CRP was positive in 75 patients and 59 of patients showed Positive blood culture. CRP test showed 80.8% sensitivity and 40.7% specificity, considering blood culture is a gold standard method. A predominate organism is Staphylococcus species followed by Escherichia coli. Mortality rate was 14%, the main isolates in nonsurvival were gram-negative bacteria.
Conclusion
Conclusion: CRP remains a rapid inflammatory marker for screening of neonatal sepsis in the absence of negative blood culture especially in low resources country.
MORBIDITY AND MORTALITY AMONGST INFANTS OF DIABETIC MOTHERS ADMITTED INTO A NEONATAL INTENSIVE CARE UNIT IN THE UNIVERSITY OF TRIPOLI TEACHING HOSPITAL
Abstract
Background
Diabetes Mellitus is the most common medical complication in pregnancy. It affects about 1 to 5% of all pregnancies. Diabetes in pregnancy is linked to several maternal and fetal/ neonatal complications.
Objectives
To determine the prevalence of perinatal morbidity and mortality pattern amongst infants of diabetic mothers.
Methods
A hospital-based retrospective cohort study performed at the University Hospital of Tripoli. Structured questionnaire used to collect relevant information and data from pre-registered medical records of 140 infants of diabetic mothers( IDMs) admitted to NICU (Januray 2013-December 2014). Maternal data were also retrieved from records( maternal parity, age, mode of delivery, maternal hypertension and management of DM). Data were coded and analyzed by using SPSS version 24. Statistical level of significance was set at a p-value of (<0.05).
Results
A total of 140 IDMs was included in the study, 118 cases born by Caesarian section(C/S), of which (63.6%) born by emergency C/S (EMC/S). The mean gestational age of IDMs was35.9±2.3 weeks and mean birth weight was3197±1042(g). The comments morbidities were respiratory distress (73.6%), hypoglycemia(45%), hypocalcemia (32.1%) macrosomia(23.6%), impaired fetal growth(13.6%)and hyperbilirubinemia(14.3%). Mortality rate was 13 (9.3%); 8 of them were had CHD (Table). Congenital anomalies account for (24.3%), congenital heart disease(CHD) was the most significant morbidity affecting the outcome(p-value= 0.0001).
Conclusion
CHD was the commonest neonatal morbidity and mortality amongst infants of diabetic mothers. The burden of IDMs is high in this study which gives an urgent message in a national base to decrease complications associated with IDMs.
Presenter of 2 Presentations
C-REACTIVE PROTEIN EVALUATION IN DIAGNOSIS OF NEONATAL SEPSIS
Abstract
Background
Background: C - reactive protein (CRP) detection is a nonspecific response to neonatal sepsis, but along with clinical symptoms is helpful, it is an early inflammatory marker, and readily available, less costly makes it an easy test to screen for neonatal sepsis especially in developing countries.
Objectives
Objective: The purpose of this study is to evaluate the early detection of CRP and its correlation to blood culture to diagnose neonatal sepsis.
Methods
Methods: The study was conducted in the special care baby unit at the University Hospital of Tripoli (Tripoli Medical Centre) on the period (January 2013 –December2014). Data of 100 neonates under clinical diagnosis of sepsis were reviewed retrospectively. .Blood culture was sent for all neonates, CRP was done quantitatively by rapid latex agglutination method and cut off value of CRP was taken as 6mg/l. Data analysis was carried out by SPSS version 25 and a p-value < 0.05 considered as statistically significant.
Results
Out of 100 patients studied 70% were above 2.500 g, 72% were normal vaginal delivery and 45% presented with fever. CRP was positive in 75 patients and 59 of patients showed Positive blood culture. CRP test showed 80.8% sensitivity and 40.7% specificity, considering blood culture is a gold standard method. A predominate organism is Staphylococcus species followed by Escherichia coli. Mortality rate was 14%, the main isolates in nonsurvival were gram-negative bacteria.
Conclusion
Conclusion: CRP remains a rapid inflammatory marker for screening of neonatal sepsis in the absence of negative blood culture especially in low resources country.
MORBIDITY AND MORTALITY AMONGST INFANTS OF DIABETIC MOTHERS ADMITTED INTO A NEONATAL INTENSIVE CARE UNIT IN THE UNIVERSITY OF TRIPOLI TEACHING HOSPITAL
Abstract
Background
Diabetes Mellitus is the most common medical complication in pregnancy. It affects about 1 to 5% of all pregnancies. Diabetes in pregnancy is linked to several maternal and fetal/ neonatal complications.
Objectives
To determine the prevalence of perinatal morbidity and mortality pattern amongst infants of diabetic mothers.
Methods
A hospital-based retrospective cohort study performed at the University Hospital of Tripoli. Structured questionnaire used to collect relevant information and data from pre-registered medical records of 140 infants of diabetic mothers( IDMs) admitted to NICU (Januray 2013-December 2014). Maternal data were also retrieved from records( maternal parity, age, mode of delivery, maternal hypertension and management of DM). Data were coded and analyzed by using SPSS version 24. Statistical level of significance was set at a p-value of (<0.05).
Results
A total of 140 IDMs was included in the study, 118 cases born by Caesarian section(C/S), of which (63.6%) born by emergency C/S (EMC/S). The mean gestational age of IDMs was35.9±2.3 weeks and mean birth weight was3197±1042(g). The comments morbidities were respiratory distress (73.6%), hypoglycemia(45%), hypocalcemia (32.1%) macrosomia(23.6%), impaired fetal growth(13.6%)and hyperbilirubinemia(14.3%). Mortality rate was 13 (9.3%); 8 of them were had CHD (Table). Congenital anomalies account for (24.3%), congenital heart disease(CHD) was the most significant morbidity affecting the outcome(p-value= 0.0001).
Conclusion
CHD was the commonest neonatal morbidity and mortality amongst infants of diabetic mothers. The burden of IDMs is high in this study which gives an urgent message in a national base to decrease complications associated with IDMs.