Rudzani Muloiwa trained as a paediatrician at the Red Cross War Memorial Children’s Hospital (RCCH) and the University of Cape Town (UCT), obtaining a Fellowship in Paediatrics with the Colleges of Medicines of South Africa (CMSA) in 2004. After this he completed an M.Sc. (Public Health Developing Countries) at the London School of Hygiene & Tropical Medicine (LSHTM). He has an interest in infectious diseases with a special emphasis on vaccine preventable diseases (his PhD explored the epidemiology of pertussis in children). From August 2015 until October 2020 Rudzani, served as the Chief clinician and Director of the Paediatric and Adolescent HIV Clinical Services at Groote Schuur Hospital, a position he left in November 2021 to assume the role of Professor and Head of Department of Paediatrics & Child Health at UCT and the RCCH. Previously he has served as both Assistant Dean for Undergraduate Student Affairs and as Acting Deputy Dean of the Faculty of Health Sciences at UCT. He is a current member of the Vaccines for Africa Initiative (VACFA) which is located within Faculty of Health Sciences at UCT. Since 2017 Rudzani serves as a member of the South Africa National Immunisation Technical Advisory Group (NAGI) and a steering committee member of the Global Pertussis Initiative (GPI). Recently he has been appointed a member of the Covid-19 Vaccine Ministerial Advisory Committee (VMAC) for South Africa.