The epidemic response for pregnant women, children, and adolescents continues to fall drastically short of 2020 super-fast-track targets set to achieve the SDG goal of ending the AIDS epidemic. Donor and country funding are constrained and likely will be insufficient, and new and emerging needs related to chronic disease and pandemic response may further burden health, social welfare, social protection, education, and economic development systems. Some of the key barriers to achieve the super-fast-track and SDG targets include, assumptions that mother-to-child transmission has been solved, missed opportunities to diagnose and treat children, and difficulty reaching and retaining the highest risk adolescents. This session explores opportunities to accelerate access to ART for children and adolescents, catalytic technologies for HIV diagnosis, and how data can help prioritize and target the HIV response.