Professor Werner Hacke was Professor and Chairman of the Department of Neurology in Heidelberg from 1987 until 2014 and is nowthe first Senior Professor in Medicine at the Ruprecht Karl´s University Heidelberg, Germany. He graduated in Medicine at the medical school oft he Aachen Technical University (RWTH) and also holds a Masters degree in Psychology. Prof Hacke had a leading role in the development of Neurological Critical Care, acute stroke management and Stroke Unit care, intra-arterial and intravenous thrombolytic therapy and has pioneered hypothermia and decompressive surgery for malignant MCA-infarction. Prof Hacke was the recipient of the Yamanouchi Europe research Award, the first non-US recipient of the „Feinberg Award for excellence in stroke research“, given by the American Stroke Association (1998), and the first recipient of the Karolinska Stroke Award, Stockholm, Sweden in 2004, the WSO Presidents Award in 2008, the Mihara Award (Japan) and the Jarecki Award (USA) both in 2009. In 2013 he was awarded the Wepfer Award by the European stroke conference. In 2018 he received the ESO science award and in 2020 the WSO Leadership in Stroke Award. He was President of the German Neurological Society 2000-2002 and the President of the German Intensive Care Society 2002-2004. He was the founding President of the European Stroke Organization (ESO) and is now its Honorary President. He is Honorary Member of the German Neurological Society, the German Stroke Society, both the German Society of Neurosurgery and the German Society of Neuroradiology, a Honorary Fellow of American Neurological Association (ANA), and a Honorary President of Neurocritical Care Society (NCS). Dr. Hacke is a Member of the Heidelberg Academy of SciencesHe holds honorary doctor degrees given by the State University of Georgia (Tblisi, Georgia) and the University of Debrecen, Hungary. Dr. Hacke was and is involved with many clinical studies, both industry-supported and investigator driven. Recently he lead studies such as ECASS I-IV, AbESTT I and II, DIAS I and II, CHARISMA, DESTINY and DESTINY II, SPACE I and II, ROCKET AF, and others as chair or co-chair of the steering committees. Werner Hacke has published more than 500 articles listed in pubmed. His h-index is 151 (google-scholar citations). With almost 200,000 citations (July 2029) he is one of the most frequently cited Clinical Neurologist worldwide. He was a "highly cited researcher" by Thomson Reuter for several years) including 2018-2020.