Dominique A. Cadilhac (Australia)
Monash University
Department of Medicine, School of Clinical Sciences at Monash Health
​Professor Dominique Cadilhac (PhD, MPH, BN, RN, FESO, FWSO) is Head: Translational Public Health and Evaluation Division, Stroke and Ageing Research, Department of Medicine at School of Clinical Sciences at Monash Health, Monash University, Australia. She is the Data Custodian for the Australian Stroke Clinical Registry at the Florey Institute of Neuroscience and Mental Health and an NHMRC Senior Research Fellow. She has published over 200 articles related to stroke research.

Presenter of 1 Presentation

 Congress Calendar

LONG-TERM MORTALITY AFTER ADMISSION FOR STROKE BETWEEN 2010-2020: OBSERVATIONAL DATA FROM THE AUSTRALIAN STROKE CLINICAL REGISTRY

Session Name
0580 - FREE COMMUNICATIONS 03: PROGNOSIS I (ID 245)
Session Type
Recovery
Date
Wed, 26.10.2022
Session Time
10:00 - 11:30
Room
Nicoll 2-3
Presenter
Lecture Time
10:10 - 10:20

Abstract

Background and Aims

Data regarding temporal changes in mortality is useful to assess impacts from improvements to stroke care. We assessed changes in 1-year and 5-year survival after stroke using data from the Australian Stroke Clinical Registry (AuSCR).

Methods

The AuSCR is used to monitor the quality of acute care and outcomes for patients admitted with stroke, with annual linkage to national death registrations. Data for direct admissions (e.g. excluded transfers/in-hospital stroke) between 2010 (8 hospitals) and 2020 (62 hospitals) were evaluated for adults aged 18+ years and by stroke type (ischaemic or intracerebral haemorrhage [ICH]). Multivariable Cox proportional hazards regression was used to evaluate differences in 1-year and 5-year survival between years.

Results

Overall 94,780 adult admissions (72 hospitals) were assessed (mean age 73 years, 55% male, 66% ischaemic). The proportion who died within 1 year was 19% (range: 23% in 2012 to 14% in 2020; and within 5 years 44% (2010: 47% and 2014: 41%). More people died following ICH (1 year: 42%; 5 years: 63%) than ischaemic stroke (1 year: 19%; 5 years 45%). Adjusted hazard of death at 1 year was significantly different between 2010 and 2020 (hazard ratio [HR]: 0.65, 95%CI 0.57, 0.74) which was explained by ischaemic stroke (hazard ratio 2020: 0.58, 95%CI 0.50, 0.68) and not ICH (HR: 0.97, 95%CI 0.73, 1.28. There were similar findings for 5-year hazard of death (ischaemic HR: 0.84, 95%CI 0.75, 0.94, ICH non-significant).

Conclusions

Within Australia, 1-year and 5-year mortality after stroke has declined over 10 years, explained by improved survival after ischaemic stroke.

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