Bereket Duko (Australia)
Curtin University
School of Population Health
Bereket Duko is currently a PhD candidate in the School of Population Health, Curtin University, Western Australia and an assistant professor at the Faculty of Health Sciences, Hawassa University, Ethiopia. He is an energetic young researcher in the area of prenatal epidemiology. His research interests are longitudinal studies on maternal and child health, mental health epidemiology, systematic review and meta-analysis. He is also interested in longitudinal studies that link prenatal alcohol, tobacco, and other drug use to mental health, substance use and physical health problems in offspring. Since 2015, he has published over 45 research articles in peer-reviewed international journals. He has committed to supporting research through acting as an Associate Editor, Guest Editor and potential reviewer for epidemiological studies. His commitment to excellence has been recognized by a high distinction medal for his postgraduate studies, Curtin University Postgraduate Research Scholarship and the Raine Study Top-up Scholarship award.

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MATERNAL AND PATERNAL SMOKING DURING PREGNANCY AND RISK OF TOBACCO SMOKING IN ADOLESCENCE: FINDINGS FROM A POPULATION-BASED PROSPECTIVE COHORT STUDY

Session Name
CLINICAL TOPICS II (ID 82)
Date
05.07.2021, Monday
Session Time
08:00 AM - 09:00 AM
Room
On-Demand 1 Slide 5 Mins
Presenter
Lecture Time
08:15 AM - 08:20 AM
Session Icon
On Demand

Abstract

Abstract Body

Background

Compelling, although inconsistent, epidemiological evidence suggests an association between maternal tobacco smoking during pregnancy and an increased risk of tobacco smoking in offspring. The aim of this study was to test the link between maternal tobacco smoking during pregnancy and the risk of tobacco smoking in offspring at the age of 17 years using paternal tobacco smoking during pregnancy as a negative control for intrauterine exposure.

Methods

Study participants were from the Raine Study, a prospective birth cohort study based in Perth, Western Australia (N=2730). Tobacco smoking in adolescents was measured using a self-reported questionnaire. Log-binomial regression was used to estimate the relative risks (RRs) of tobacco smoking in offspring exposed to maternal prenatal tobacco use during the first and third trimesters of pregnancy. We have also calculated the E-values to investigate the potential effect of unmeasured confounding.

Results

After adjusting for potential confounders, we found the increased risks of tobacco smoking in offspring exposed to maternal tobacco smoking during the first trimester [RR 1.50 (95% CI: 1.13-1.97)] (E-value for point estimate=2.37) and during both trimesters of pregnancy [RR 1.41 (95% CI: 1.03-1.89)] (E-value for point estimate=2.17). However, we found insufficient statistical evidence for an association between paternal tobacco smoking during pregnancy and the risk of tobacco smoking in offspring [RR 1.18 (95% CI: 0.84-1.67)].

Conclusion

Maternal tobacco smoking during pregnancy was associated with an increased risk of tobacco smoking in offspring at the age of 17 years. Tobacco smoking cessation at the early stages of gestation may reduce the risk of tobacco smoking in offspring.

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