Welcome to the 26th WONCA Europe Virtual Conference Programme Scheduling
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Icons Legend: - Fully Live Session - On Demand with Live Q&A - Pre-Registration Required
Displaying One Session
Session organised by the International Primary Care Respiratory Group (IPCRG), the European Academy of Allergy and Clinical Immunology (EAACI) primary care working group and the General practice Research on Infections Network (GRIN)
MEDICAL TREATMENT OF COVID-19 IN GENERAL PRACTICE
So far, there are few specific treatments for COVID-19 that have been proven in rigorous clinical trials to be effective. Most cases are being managed in the community. It is essential that we urgently identify therapeutics that speed recovery and prevent the need for hospital admission. An ideal intervention would be one that is safe, with few side-effects, helps prevent disease progression, and can be administered in the community using existing processes and capability.
The Platform Randomised trial of treatmeNts in the Community for epIdemic and Pandemic iLlnEsses (PRINCIPLE) is a multicenter, open-label, multi-arm, response-adaptive platform randomized controlled trial of community treatments for COVID-19. It operates under a master protocol that allows the addition of further interventions into the trial while the trial is already in progress, so a new trial does not need to be started afresh each time an additional suitable intervention becomes available, and it also means that existing controls can be used efficiently to give rapid answers about the effectiveness of new interventions. Response adaptive randomisation allows the proportion of participants allocated to each intervention to be adjusted, based on emerging data from the trial to increase efficiency and shorten time to results. Further innovations in trial design and delivery include recruiting through general practice as well as being an ‘online’ trial, using approaches where the ‘patient comes to research’ as well as the trial ‘taking research to the patient.’
Readouts for azithromycin, doxycycline, inhaled budesonide and colchicine will be presented.
COVID-19 IN MIGRANT POPULATIONS
People with a migration background, especially those living in precarious conditions, have been severly affected by the COVID-19 pandemic. This observation reproted from various European countries highlights the relationships between circumstances of the daily life, at home, at work, in care setting and in the public domain, and health. This talk will explore some key challenges and propose tools to be applied in primary care setting to foster better health equity.