Welcome to the 22nd WCP Congress Program Scheduling
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RECORDED LECTURES
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FOREWORD
Abstract
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Ate, the Greek goddess of mischief, delusion, ‘infatuation and the rash foolishness of blind impulse’, often rooted in guilt, tempted men to do evil, and to eventual ruin. She even entrapped Zeus, but he hurled her down from the Olympus. Now Ate wanders the earth, as a kind of avenging spirit, still working her mischief among mankind, perhaps in the form of delusional disorders which continue to pose epistemological, diagnostic and treatment challenges to 21st century psychiatry. While the term was only coined in 1977, the concept of paranoia has been used for centuries. During the 17th century it was used largely as a generic term for mental illness. In 1863, Kahlbaum introduced the concept of paranoia as "a form of partial insanity, which throughout the course of the disease principally affected the sphere of the intellect" Kraepelin, viewed paranoia as an uncommon, chronic condition, differentiated from dementia praecox by the presence of fixed, non-bizarre systemized and consistent delusions, often related to real-life events, lack of deterioration over time, preserved thought processes, and relatively minimal involvement of affect and volition. Little has changed since and the diagnosis hovers uneasily on the fringes of psychotic disorders. Given the ability to rationalise their delusions, many patients slip under the radar for years before reaching crisis point when they finally receive treatment, usually after being ‘sectioned’. Epidemiological data are inadequate and major epistemological issues, including treatment and prognosis remain unresolved. It is proposed to review the available evidence and explore future directions.
EPIDEMIOLOGY, DIAGNOSIS AND AETIOLOGY
COURSE, TREATMENT, PROGNOSIS
Abstract
Abstract Body
The diagnosis of paranoia/delusional disorder has been significantly modified and redefined from DSM-III to DSM-5, which in turn also meaningfully differs from the ICD-10 criteria. Delusional disorder is rarely studied as a separate entity; most drug studies subsume delusional disorder as one in a range of psychotic spectrum disorders, and no sound randomized clinical trials for delusional disorder appear in the literature. Further, the disorder itself is rather poorly defined, and the ability to make a distinction between variants of delusional disorder or between delusional disorder and other forms of mental disorder may be clinically challenging There is currently insufficient evidence to make evidence-based recommendations for treatments of any type for people with delusional disorder. Until such evidence is found, the treatment of delusional disorders will most likely include those that are considered effective for other psychotic disorders and mental health problems. It seems reasonable to offer treatments that have efficacy in other psychotic disorders. Delusional disorder is relatively uncommon and has been regarded as notoriously difficult to treat with any intervention. This has likely curbed efforts to study effective treatments more systematically, although some newer evidence suggests that certain drugs may be more efficacious than earlier agents. However, given the treatment-resistant nature and the complexities in psychopathology involved, the need for a comprehensive management plan is discussed. Prognostic unfavorable variables including systematization of delusions, severe preoccupation with present delusions, and no suspicion of attempt at concealment of delusions and hallucinations are discussed