Welcome to the 22nd WCP Congress Program Scheduling

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RECORDED LECTURES

Icon Legend: Pre-Recorded & Scheduled On-Demand  

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Displaying One Session

STATE OF THE ART SYMPOSIUM
Session Type
STATE OF THE ART SYMPOSIUM
Date
Thu, 04.08.2022
Session Time
19:30 - 20:30
Room
ONLINE HALL E
Session Description
This session represents an interface of areas of basic and clinical research in dementia. Speakers will be presenting selected psychiatric clinical and biological research on factors affecting cognitive functions, leading to dementia, commonly with neuropsychiatric symptoms like psychosis. Kasia Gustaw Rothenberg will focus on Lewy body diseases and psychosis in their course. She will discuss clinical, cognitive and genetic correlations of psychosis in Lewy body diseases. Jerzy Leszek will discuss insulin resistance in AD. Recent studies reveal the impact of p53 on expression and processing of several microRNA/miRNA. Additionally, the role of miRNAs in promotion of insulin resistances and in type 2 diabetes have been well documented. Understanding p53/miRNA crosstalk in driving insulin resistance in Alzheimer’s brains could lead to effective diagnostic and therapeutic diagnostic and lead to development of therapy Carlos Augusto de Mendonça Lima will on psychosis in older adults, and underlines which assessments and managements are required at primary care level. He also takes into account the possible impact of the new Diagnostic Classifications on the approach of psychosis in older adults, in particular in what concerns the organization of care and the reduction of all forms of stigma and discrimination against older adults. The Chair and Co-Chair will frame of these findings within translational model of psychiatric disorders and discuss their implication for a personalized medicine approach to treatment

INSULIN RESISTANCE IN ALZHEIMER'S DISEASE: ROLE OF P53 AND MICRORNAS

Date
Thu, 04.08.2022
Session Time
19:30 - 20:30
Session Type
STATE OF THE ART SYMPOSIUM
Lecture Time
19:30 - 19:45
Room
ONLINE HALL E

CLINICAL, COGNITIVE AND GENETIC CORRELATES OF PSYCHOTIC SYMPTOMS IN LEWY BODY DISEASES

Date
Thu, 04.08.2022
Session Time
19:30 - 20:30
Session Type
STATE OF THE ART SYMPOSIUM
Lecture Time
19:45 - 20:00
Room
ONLINE HALL E

PSYCHOTIC SYMPTOMS IN DEMENTIA

Date
Thu, 04.08.2022
Session Time
19:30 - 20:30
Session Type
STATE OF THE ART SYMPOSIUM
Lecture Time
20:00 - 20:15
Room
ONLINE HALL E

Abstract

Abstract Body

There is an increase of the prevalence of psychotic symptoms in older adults. The presence at this period of life of the highest comorbidy rate, the changes of the central nervous system with ageing and the particular high frequency of life stressors during this period of life may all explain this. Psychotic symptoms are present in an important number of medical and psychiatric conditions and they make part of psychotic disorders in late life too. The same classification of disorders with psychotic symptoms in adults may be used for older adults. But the proposed classification presented, with the respective diagnostic criteria, may quickly changes next years with the publication in of the International Classification of Diseases, 11th revision, to which a working group of old age psychiatrists was invited to review the classification of psychotic disorders. A consensus statement proposed in 19981, in an arbitrary way, cut-offs with potential clinical and research utility. Psychosis diagnosed before 40 years should be classified as having an early onset; psychosis diagnosed between 40 and 60 years should be recognized as having a late onset. Psychosis diagnosed by the first time after 60 years should be recognized as having a very late onset.

Primary psychotic symptoms exist in persistent psychotic disorders (schizophrenia, delusional disorder, schizoaffective disorder), acute psychotic disorder and personality disorders (paranoid, schizoid and schizotypal personality disorders). Secondary psychotic symptoms include major and minor neurocognitive disorders, delirium, organic mental disorders, disorders due to psychoactive substance use, bipolar disorders and depressive episode. Somatic disorders and comorbidities, and iatrogenic causes included at this cluster. Assessment and management of psychosis in older adults at Primary Care require an organization of the mental health care system. The management of psychosis in older adults implies the proper use of multidisciplinary therapeutic interventions: pharmacotherapy and psychological, social and occupational therapy. All forms of stigma and discrimination against older adults with psychosis and their carers should be eliminated.

Howard R, Rabins PV, Seeman MV, Jeste DV and the International Late-Onset Schizophrenia Group. Late-Onset Schizophrenia and Very-Late-Onset Schizophrenia-Like Psychosis: an international consensus. Am J Psychiatry 2000; 157; 172-178.

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