Consultation-Liaison Psychiatry has evolved its neurobiological formulation with the rise of the HIV/AIDS pandemic. Ever since, there has been a robust integration of both inpatient and outpatient services to better serve highly complex cases of people living with HIV (PLWHIV), who develop unique syndemic manifestations.
In this presentation, we will review how lessons learned from the HIV/AIDS pandemic propelled a rapid organization and transition of healthcare systems to better serve patients suffering from COVID-19, as well as how the practice of consultation-liaison psychiatry evolved to address unique challenges faced by PLWHIV such as stigma, comorbid syndemic conditions, among others to provide integrated care for people living with long COVID-19 symptoms (also known as Post-Acute Sequelae of SARS CoV-2 infection, PASC).