Welcome to the WCN 2021 Interactive Program
The congress will officially run on Central European Time (CET) - Rome Time
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Please note that all sessions will run at their scheduled time and be followed by a LIVE Q&A/Discussion at the end
The viewing of sessions, cannot be accessed from this conference calendar. All sessions are accessible via the Virtual Platform
- Bruno Dubois (France)
UPDATE IN POSTERIOR CORTICAL ATROPHY
- Sebastian Crutch (United Kingdom)
Abstract
Abstract Body
Posterior cortical atrophy (PCA) is a rare neurodegenerative syndrome that primarily affects the parietal and occipital lobes and is typified by striking early deficits in higher visuospatial processing, numeracy and literacy. In this talk we will review recent developments in the clinical, cognitive, imaging, pathological and genetic characterisation of the syndrome. Linked to recent increased interest in biological subtypes of AD, we will also consider heterogeneity within the PCA syndrome and overlap with related clincial presentations, and the broad notion of PCA as an extreme point in a continuum of phenotypical variation. Finally we will examine the changing and distinctive care, management and support needs of those living with PCA and look at promising non-pharmarcological interventions and strategies.
THE DIFFERENT FORMS OF PRIMARY PROGRESSIVE APHASIAS
- Maria Luisa Gorno-Tempini (United States of America)
NEUROIMAGING APPROACH OF ATYPICAL FORMS OF ALZHEIMER’S DISEASE
- Federica Agosta (Italy)
Abstract
Abstract Body
Alzheimer’s disease (AD) is not a unitary clinical syndrome. Patients with early age-of-onset AD can present with multi-domain cognitive impairment at onset. This cognitive picture is very different from the typical profile of late-onset patients with progressive memory deficit as the central feature. AD can also present as atypical, relatively focal clinical syndromes, more frequently associated with early age-of-onset, i.e., as posterior cortical atrophy (PCA) and logopenic variant of primary progressive aphasia (lvPPA). Neuroimaging, including magnetic resonance imaging (MRI) and positron emission tomography (PET), is playing an increasingly important role in the study of atypical forms of AD, delineating the structural and functional brain alterations associated with these conditions. Neuroimaging patterns acquired at the prodromal stage can discriminate between AD and other neurodegenerative diseases and among AD variants. Advanced MRI techniques are of special interest for their potential to characterize the signature of each neurodegenerative condition and aid both the diagnostic process and the monitoring of disease progression. All these findings will become crucial when disease-modifying (personalized) therapies will be established.