Full Professor of Respiratory Medicine at the University of Pisa, and Chief of the Respiratory Pathophysiology and Pulmonary Rehabilitation Unit of the University Hospital of Pisa, up to November 2018. Graduated in Medicine and Surgery at the University of Pisa in 1972, He post-graduated in Occupational Medicine (1974), Respiratory Medicine (1977) and Allergy and Clinical Immunology (1981). Post-doctoral fellowships at the University of British Columbia (Vancouver, Canada, 1985 and 1987) and at the S. Francisco General Hospital (S. Francisco, Ca, USA, 1989). Research fields: pathophysiology and therapy of asthma and COPD, occupational asthma, airway pharmacology, pulmonary rehabilitation. Co-authors of 320 papers on peer-review journals, on the topics of asthma and COPD. Principal investigator of several phase 2-phase 3 clinical trials in asthma, COPD and bronchiectasis, and director of several research projects funded by Italian Ministry of Health, Italian Agency of the Drug (AIFA), Tuscany Region and pharmaceutical companies. Between 2005 and 2015, He was member of the Board of Directors of GINA International, and Chairman of the GINA Mediterranean Initiative. Up to now, He is the Chairman of the GINA Italy Initiative. He is a fellow of European Respiratory Society.