Maria Deloria Knoll, PhD, is the Director of Epidemiology at the International Vaccine Access Center (IVAC) at the Johns Hopkins Bloomberg School of Public Health. Dr. Knoll’s work involves policy-driven research and synthesis of global evidence to evaluate vaccines and vaccine-preventable diseases and are generally collaborative efforts involving WHO, CEPI and other institutions worldwide. Recent projects include: the PSERENADE study that evaluates impact of PCV10/13 introduction globally on IPD in all ages; VIEW-Hub.org, a publicly available platform displaying PCV introduction, coverage, access, impact, and pneumococcal disease burden data globally (and for 7 other vaccines); evaluating impact of PCV dosing schedule, age at immunization and product on pneumococcal carriage, immunogenicity and disease; estimating the global disease burden and serotype distribution of pneumococcus, Hib, meningococcus and pertussis; the PERCH study that estimated pneumonia etiology in 7 developing country settings; evaluating new diagnostic tools, such as determining sensitivity and specificity of antigen-based blood tests and pneumococcal serotype-specific urine antigen tests; evaluating new digital tools to standardize clinical findings, such as digital auscultation and computer automated chest x-ray interpretation; developing improved analytical methods for estimating pneumonia etiology; global review and synthesis of effectiveness, safety and neutralizing antibody responses of COVID-19 vaccines.