EVOLUTION OF INVASIVE PNEUMOCOCCAL DISEASE (IPD) BURDEN AND THE POTENTIAL EFFECT OF UNIVERSAL PNEUMOCOCCAL VACCINATION IN BOGOTÁ, COLOMBIA (ID 740)
- Luis Felipe Reyes, Colombia
- Diego F. Severiche, Colombia
- David F. Severiche, Colombia
- Paula C. Ramirez Valbuena, Colombia
- S.L Gómez, Colombia
- Katherine Carvajal,
- Alirio Bastidas, Colombia
- Edwin Silva,
- H. Vargas, Colombia
- Luis Felipe Reyes, Colombia
Abstract
Background
IPD is the leading cause of infectious death worldwide. The universal pneumococcal vaccine in children has reduced IPD burden in several countries around the world. Importantly, after vaccine introduction, different pneumococcal serotypes are more frequently identified. However, in Bogotá-Colombia, there are scares data about the effect of the pneumococcal vaccine and its burden. Therefore, this study aims to provide novel data
Methods
This is a retrospective analysis of the pneumococcal reports of a surveillance program during the last 15 years in Bogotá, Colombia. S. pneumoniae were identified in each hospital and then characterized and serotyped in a governamental centralized laboratory. Descriptive statistics were used
Results
A total of 2605 cases were analyzed. Most common serotypes were 14 (7.11%), 1 (3.13%) 6A and 6B (2.71%) before 2010. Between 2011-2019, the most common serotypes changed to 19A (14.9%), 3 (8.06%) and 6C (3.86%) (Figure-1). Importantly, there was no change in the incidence of invasive pneumococcal disease throughout the study
Conclusions
Most common serotypes were 14 (7.11%), 1 (3.13%) 6A and 6B (2.71%) before 2010. Between 2011-2019, the most common serotypes changed to 19A (14.9%), 3 (8.06%) and 6C (3.86%) (Figure-1). Importantly, there was no change in the incidence of invasive pneumococcal disease throughout the study