Streptococcus pneumonia colonization in nasopharyng consist of many serotypes, strongly related to high morbidity and mortality of pneumonia in children under-five.This study objective is to compare between S. pneumonia serotypes on nasopharyngeal carriage among children with pneumonia infection and healthy.
We collected the nasopharyngeal (NP) swab among 130 under-five years of age pneumonia children at M. Djamil hospital and healthy children as control from two daycares in Padang, respectively. Demographic and clinical data were recorded during NP swab collection.The isolate of Streptococcus pneumoniae has been performed by culture on 8% sheep-blood agar plate, were identified serotype by PCR methods.
Overall we found that 19F (21%) and untypeable Streptococcus pneumonia serotype (21%) are the most frequent from PCR identification, followed by 6C, 14 and 34 serotype. Comparing pneumonia cases and healthy children, 19F serotype (22%) more frequent among control healthy children than pneumonia cases (17%). We found untypeable and 6B serotype are the most frequent among pneumonia patiens, but not in control group.
We found the same proportion of 19F serotype Streptococcus pneumoniae among pneumonia patiens and healthy, but very high untypeable serotype in pneumonia patiens.