Tao Zhang, China
School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education Department of Epidemiology
Author Of 5 Presentations
SEROTYPE-SPECIFIC ANTIBIOTIC NON-SUSCEPTIBILITY OF THE CLINICAL PNEUMOCOCCI IN SUZHOU, CHINA (ID 636)
Session Name
Clinical Sciences - Pneumococcal Infections in Aboriginal Populations
Authors
- Changpeng Liu, China
- Shuang Feng, China
- Yunzhen Tao, China
- JIAN XUE, China
- Zirui Dai, China
- Qinghui Chen, China
- Wanqing Zhang, China
- Xinxin Xu, China
- Jianmei Tian, China
- Genming Zhao, China
- Xuejun Shao, China
- Tao Zhang, China
PREDICTING THE IMPACT OF PCV13 ON INVASIVE PNEUMOCOCCAL DISEASE (IPD) IN MAINLAND CHINA (ID 823)
Session Name
Population Sciences - Epidemiology, Economics, and Mathematical Modelling
Authors
- Billy Quilty, United Kingdom
- Yang Liu, United Kingdom
- Shuang Feng, China
- Sam Clifford, United Kingdom
- Kaile Chen, China
- Charlie Diamond, United Kingdom
- Xin Tong, China
- Hongjie Yu, China
- Mark Jit, United Kingdom
- Tao Zhang, China
- Stefan Flasche, United Kingdom
Background
China is one of few countries yet to introduce PCV. We aimed to estimate the long-term impact of a PCV13 programme on childhood IPD in mainland China, accounting for provincial heterogeneity.
Methods
A Bayesian hierarchical model was fit to systematic review data on the proportion of vaccine-type IPD and carriage in each province. A mechanistic model was then used to predict the relative reduction in IPD incidence of a PCV13 programme, assuming VT circulation is eventually interrupted and replaced by NVTs.
Results
Across China, we estimate that a median 75% (95% HDI: 53 – 90%) of carriage and 88% (95% HDI: 76 - 94%) of IPD is caused by vaccine serotypes. A mature PCV programme would lead to a median 51% (95% HDI: -40 – 81%) reduction in the incidence of IPD, ranging from 33% in Hubei (95% HDI: -34 – 76%) to a median 76% in Beijing (95% HDI: 44 – 92%). All 95% credible intervals for province-level covariate effects contain zero for VT carriage and IPD, and as such the impact estimates in provinces with little or no serotype distribution data remain uncertain.
Conclusions
PCV13 has the potential to substantially reduce the pneumococcal disease burden in China, but data to underpin the estimates is sparse in Western China.
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SEROTYPE DISTRIBUTION OF PNEUMOCOCCI ISOLATED FROM CHILDREN WITH RESPIRATION INFECTION FROM 2017 TO 2019 IN SUZHOU, CHINA (ID 568)
Session Name
Vaccines - Impact of Vaccine programs and Serotype Replacement
Authors
- Shuang Feng, China
- Changpeng Liu, China
- Yunzhen Tao, China
- JIAN XUE, China
- Zirui Dai, China
- Wanqing Zhang, China
- Xinxin Xu, China
- Yunzhong Wang, China
- Jianmei Tian, China
- Genming Zhao, China
- Xuejun Shao, China
- Tao Zhang, China
STUDY ON EPIDEMIC CHARACTERISTICS AND ANTIBIOTICS SUSCEPTIBILITY OF STREPTOCOCCUS PNEUMONIAE IN CHILDREN WITH RESPIRATORY TRACT INFECTION IN SUZHOU (ID 640)
Session Name
Clinical Sciences - Pneumococcal Infections in Aboriginal Populations
Authors
- Changpeng Liu, China
- Shuang Feng, China
- Yunzhen Tao, China
- JIAN XUE, China
- Zirui Dai, China
- WANGQING ZHANG, China
- Xinxin Xu, China
- Genming Zhao, China
- Xuejun Shao, China
- Tao Zhang, China
ESTIMATING INCIDENCE OF PNEUMOCOCCAL MENINGITIS BEFORE THE INTRODUCTION OF PCV13 IN SUZHOU, CHINA WITH CAPTURE-RECAPTURE METHOD (ID 510)
Session Name
Population Sciences - Epidemiology, Economics, and Mathematical Modelling