P-0725 - Dietary Fiber Intake and Urinary Creatinine: Methodological Implications for Epidemiological Studies
E-POSTER GALLERY (ID 409)
P-0725 - Dietary Fiber Intake and Urinary Creatinine: Methodological Implications for Epidemiological Studies
Abstract Control Number
1532
Abstract Body
Background/Aim: Creatinine is used to estimate renal function and to correct for urinary dilution. However, urinary creatinine (UCR) is determined by genetic, morphological, and lifestyle characteristics that should be accounted for to increase comparability throughout epidemiological studies. Recently, dietary fiber has been proposed as a mediator of renal function. The aim of this study was to evaluate the relationship between dietary fiber and UCR, with an eye towards methodological implications for studies that utilize UCR-corrected measurements. Methods: Available information regarding UCR, dietary fiber intake, age, and other UCR-related factors were analyzed in 801 women residing in Northern Mexico. Results: Using linear regressions, we estimated a significant age-adjusted increase of 10.04 mg/dL UCR for a 10 g/day increase in dietary fiber intake. Conclusion: Our results suggest that epidemiological studies should adjust UCR by dietary fiber intake in order to improve comparability of studies and overall accuracy.
