Dr. Simon Best is an Associate Professor of Otolaryngology – Head and Neck Surgery at Johns Hopkins School of Medicine, and a surgeon and clinician at the Johns Hopkins Voice Center. His clinical and research career focus is Human Papillomavirus (HPV)-related diseases, particularly Recurrent Respiratory Papillomatosis (RRP), an HPV-related disease that affects the voice and airway in both children and adults. He maintains a surgical practice focused on RRP, seeing patients from across the country with this rare disease, is a leading member of the national RRP Task Force, as well as working with international RRP patient organizations to bridge the gap between patient care, clinical innovations, and basic scientific research. He has spoken widely about novel treatments for RRP, especially as a leading advocate for systemic bevacizumab (Avastin) and its use in severe cases of RRP.