This will be a 90 minute session, each speaker will have 20 mins and there will be a 10 - 15 minute discussion at the end. The learning objectives focus on understanding how to bring screening and treating into health care services without loss to follow up and with wide coverage. Linking screening to immediate treatment has many advantages, but also some disadvantages, including over treatment. AVE (Automated Visual Evaluation) may have value either as a primary screening test or as a triage test - if specificity and positive predictive value are high, the problem of overtreatment will become much less of an issue. If functioning properly AVE may provide an instant diagnosis to guide on site, same day treatment. How the algorithms are developed is critical to reliability and accuracy, and this session will explore some of these issues. Recommendations will be based on real-world data. Implementation challenges will be addressed and solutions offered.