Academics 08/01/2003 – 07/01/2004 Assistant Professor of Pediatrics, University of Arkansas for Medical Sciences. 08/12/2013 – 08/1/2016 Assistant Professor of Pediatrics University of Missouri in Kansas City. 08/01/2016 – now, Associate Professor of Pediatrics, University of Missouri in Kansas City. Education 1977 – 1983 Medical School, Aristotelian University of Thessaloniki 06/24/1985 – 30/06/1988 Resident in Pediatrics, St Louis Children’s Hospital at Washington University Medical Center, St Louis, Missouri, USA 07/01/1988 – 30/06/1991 Fellow in Pediatric Cardiology, Duke University Medical Center, Durham, N. Carolina, USA 07/01/1991 – 30/07/1992 Fellow in Cardiac Pathology, Children’s Hospital, Harvard Medical School, Boston, USA 09/01/1995 – 08/31/1996 Fellow in Pediatric Cardiac Electrophysiology, Duke University Medical Center, Durham, USA PhD/ Thesis 2004 University of Patras, Greece: “Definitive treatment of supraventricular tachycardia in children with radiofrequency current.” Board Certification 05/10/1990 General Pediatrics certificate, Thessaloniki, Greece 02/06/1989 Diplomate, American Board of Pediatrics 11/10/1991, Recertified 6/2014 Diplomate, American Board of Pediatrics and Sub-Board of Pediatric Cardiology 12/2014 International Board of Heart Rhythm Examiners: Certification in Clinical Electrophysiology, Pediatric Electrophysiology 08/2015 International Board of Heart Rhythm Examiners: Certification Cardiac Rhythm Device Specialist Editorial Boards AD-HOC REVIEWER for peer-reviewed international journals: Circulation, PACE, Europace, Heart Rhythm, Heart Rhythm Case Reports, Cardiology in the Young Professional Experience 09/01/1992 – 11/30/1993 Pediatric Cardiologist, Athens Medical Center, Athens, Greece. 12/01/1993 – 12/31/1997 Attending Pediatric Cardiologist, Onassis Cardiac Surgery Center, Athens, Greece. From 09/01/1995-08/31/1996 Leave of absence for training in Pediatric Electrophysiology. 01/01/1998-07/30/2003 Associate Director, Division of Pediatric Cardiology, Onassis Cardiac Surgery Center, Athens, Greece 08/01/2003 – 07/01/2004 Director, Pediatric Electrophysiology, Division of Cardiology, Arkansas Children’s Hospital, Little Rock, Arkansas, USA 07/01/2004 – 12/31/2007 Associate Director, Division of Pediatric Cardiology and Director of Pediatric Electrophysiology, Onassis Cardiac Surgery Center, Athens, Greece 1/1/2008-7/30/2013 Director, Pediatric Cardiology and Electrophysiology, Mitera Children’s Hospital, Athens, Greece 08/12/2013 – now Director of Electrophysiology, Division of Pediatric Cardiology, Department of Pediatrics, Children’s Mercy Hospital, Kansas City, Missouri, USA. Professional Society Membership 1994 – now, Association of European Pediatric Cardiologists 1992 – now, Hellenic Society of Pediatric Cardiology 1994 – now, Hellenic Society of Pediatrics 1993 – now, Hellenic Society of Cardiology 2002 – 2004 President of Working Group of Congenital Heart Disease of the HSC 1999 – now, Pediatric and Congenital Electrophysiology Society: October 2000 – now, Cardiac Electrophysiology Society Heart Rhythm Society: Member since 2003 – now, Fellow of Heart Rhythm Society (FHRS). American Heart Association: Premium Professional Member, 2014-now. Clinical Interests Pediatric Electrophysiology: transcatheter ablation of supraventricular and ventricular arrhythmias (using both radiofrequency and cryoablation) with the use of 3D mapping non-fluoroscopic techniques; pacemaker and defibrillator implantation and follow-up; non-invasive electrophysiology testing; tilt-table testing; investigation and follow-up of genetic arrhythmia syndromes (Long QT, Catecholaminergic Polymorphic Ventricular Tachycardia, Brugada syndrome, Hypertrophic and Dilated Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy) . General Pediatric Cardiology: Clinical cardiology, echocardiography, cardiac catheterization in infants, children, adolescents and adults with congenital heart disease. Research Interests Pediatric Cardiology: New clinical and diagnostic findings in Congenital Heart Disease. Cardiac Pathology: Clinical-pathologic correlations, with echocardiographic and angiocardiographic findings in congenital heart disease. Pediatric Cardiac Electrophysiology and Pacing: Effects of radiofrequency lesions on the immature myocardium. Treatment of pediatric cardiac arrhythmias with radiofrequency ablation. Non-fluoroscopic imaging in pediatric catheter ablation. Cryoablation in the treatment of pediatric arrhythmias. Treatment of postoperative cardiac arrhythmias in patients with congenital heart disease with radiofrequency ablation. Impact of the permanent ventricular pacing site on left ventricular function in children Cardiac Resynchronization in Children and Patients with Congenital Heart Disease. New clinical and molecular genetic findings in patients with genetic arrhythmia syndromes. Abstracts and Publications 88 Abstracts in national and international meetings 62 publications in peer-reviewed journals 6 chapters in books Recent Publications Calmodulin mutations and life-threatening cardiac arrhythmias: insights from the International Calmodulinopathy Registry. Crotti L, Spazzolini C, Tester DJ, Ghidoni A, Baruteau AE, Beckmann BM, Behr ER, Bennett JS, Bezzina CR, Bhuiyan ZA, Celiker A, Cerrone M, Dagradi F, De Ferrari GM, Etheridge SP, Fatah M, Garcia-Pavia P, Al-Ghamdi S, Hamilton RM, Al-Hassnan ZN, Horie M, Jimenez-Jaimez J, Kanter RJ, Kaski JP, Kotta MC, Lahrouchi N, Makita N, Norrish G, Odland HH, Ohno S, Papagiannis J, Parati G, Sekarski N, Tveten K, Vatta M, Webster G, Wilde AAM, Wojciak J, George AL, Ackerman MJ, Schwartz PJ. Eur Heart J. 2019 Jun 6. pii: ehz311. A pore-localizing CACNA1C-E1115K missense mutation, identified in a patient with idiopathic QT prolongation, bradycardia, and autism spectrum disorder, converts the L-type calcium channel into a hybrid nonselective monovalent cation channel. Ye D, Tester DJ, Zhou W, Papagiannis J, Ackerman MJ. Heart Rhythm. 2019 Feb;16(2):270-278. Atrioventricular Nodal Reentrant Tachycardia in Patients with Congenital Heart Disease: Outcome after Catheter Ablation. Papagiannis J, Beissel DJ, Krause U, Cabrera M, Telishevska M, Seslar S, Johnsrude C, Anderson C, Tisma-Dupanovic S, Connelly D, Avramidis D, Carter C, Kornyei L, Law I, Von Bergen N, Janusek J, Silva J, Rosenthal E, Willcox M, Kubus P, Hessling G, Paul T; Pediatric and Congenital Electrophysiology Society. Circ Arrhythm Electrophysiol. 2017 Jul;10(7). PACES/HRS expert consensus statement on the use of catheter ablation in children and patients with congenital heart disease: Developed in partnership with the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). Endorsed by the governing bodies of PACES, HRS, the American Academy of Pediatrics (AAP), the American Heart Association (AHA), and the Association for European Pediatric and Congenital Cardiology (AEPC). Philip Saul J, Kanter RJ; WRITING COMMITTEE, Abrams D, Asirvatham S, Bar-Cohen Y, Blaufox AD, Cannon B, Clark J, Dick M, Freter A, Kertesz NJ, Kirsh JA, Kugler J, LaPage M, McGowan FX, Miyake CY, Nathan A, Papagiannis J, Paul T, Pflaumer A, Skanes AC, Stevenson WG, Von Bergen N, Zimmerman F. Heart Rhythm. 2016 Jun;13(6):e251-89. Management of paediatric arrhythmias in Europe. Happonen JM, Blom N, Celiker A, Drago F, Hebe J, Janousek J, Kornyei L, Kriebel T, Papagiannis J, Paul T, Pfammatter JP, Rosenthal E, Tuzcu V. Europace. 2015 Dec;17(12):1879. Permanent junctional reciprocating tachycardia in children: a multicenter experience. Kang KT, Potts JE, Radbill AE, La Page MJ, Papagiannis J, Garnreiter JM, Kubus P, Kantoch MJ, Von Bergen NH, Fournier A, Côté JM, Paul T, Anderson CC, Cannon BC, Miyake CY, Blaufox AD, Etheridge SP, Sanatani S. Heart Rhythm. 2014 Aug;11(8):1426-32. Transcatheter valve-in-valve implantation in the tricuspid position. Tzifa A, Momenah T, Al Sahari A, Al Khalaf K, Papagiannis J, Qureshi SA. EuroIntervention. 2014 Dec;10(8):995-9. Cryoablation of atrioventricular nodal reentrant tachycardia in children and adolescents: improved long-term outcomes with increasing experience. Cokkinakis C, Avramidis D, Alexopoulos C, Kirvassilis G, Papagiannis J. Hellenic J Cardiol. 2013 May-Jun;54(3):186-91. Calmodulin mutations associated with recurrent cardiac arrest in infants. Crotti L, Johnson CN, Graf E, De Ferrari GM, Cuneo BF, Ovadia M, Papagiannis J, Feldkamp MD, Rathi SG, Kunic JD, Pedrazzini M, Wieland T, Lichtner P, Beckmann BM, Clark T, Shaffer C, Benson DW, Kääb S, Meitinger T, Strom TM, Chazin WJ, Schwartz PJ, George AL Jr. Circulation. 2013 Mar 5;127(9):1009-17. Permanent cardiac pacing in children: choosing the optimal pacing site: a multicenter study. Janoušek J, van Geldorp IE, Krupičková S, Rosenthal E, Nugent K, Tomaske M, Früh A, Elders J, Hiippala A, Kerst G, Gebauer RA, Kubuš P, Frias P, Gabbarini F, Clur SA, Nagel B, Ganame J, Papagiannis J, Marek J, Tisma-Dupanovic S, Tsao S, Nürnberg JH, Wren C, Friedberg M, de Guillebon M, Volaufova J, Prinzen FW, Delhaas T; Working Group for Cardiac Dysrhythmias and Electrophysiology of the Association for European Pediatric Cardiology. Circulation. 2013 Feb 5;127(5):613-23 Impact of the permanent ventricular pacing site on left ventricular function in children: a retrospective multicentre survey. van Geldorp IE, Delhaas T, Gebauer RA, Frias P, Tomaske M, Friedberg MK, Tisma-Dupanovic S, Elders J, Früh A, Gabbarini F, Kubus P, Illikova V, Tsao S, Blank AC, Hiippala A, Sluysmans T, Karpawich P, Clur SA, Ganame X, Collins KK, Dann G, Thambo JB, Trigo C, Nagel B, Papagiannis J, Rackowitz A, Marek J, Nürnberg JH, Vanagt WY, Prinzen FW, Janousek J; Working Group for Cardiac Dysrhythmias and Electrophysiology of the Association for European Paediatric Cardiology. Heart. 2011 Dec;97(24):2051-5. Radiofrequency ablation of accessory pathways in children and congenital heart disease patients: impact of a nonfluoroscopic navigation system. Papagiannis J, Avramidis D, Alexopoulos C, Kirvassilis G. Pacing Clin Electrophysiol. 2011 Oct;34(10):1288-396.