M. Neubauer (Krems, AT)

Center for Regenerative Medicine and Orthopedics
Markus Neubauer is a resident physician at the Department for Orthopedics; University Hospital Krems; Austria; Head of department: Prim. Univ.-Prof. Dr. Florian Gottsauner) and simultaneously conducted a PhD on „Regenerative Medicine in Cartilage repair“ at the Center for Regenerative Medicine at the Danube University Krems (Head of department: Univ.-Prof. Dr. Stefan Nehrer).

Presenter Of 1 Presentation

Poster Osteoarthritis

P153 - Artificial Intelligence in Radiographic Diagnostics in Correlation with Clinical Scores in Knee Osteoarthritis Patients

Presentation Topic
Osteoarthritis
Date
13.04.2022
Lecture Time
09:30 - 09:30
Room
Exhibition Foyer
Session Name
7.3 - Poster Viewing / Coffee Break / Exhibition
Session Type
Poster Session
Disclosure
MN, AS, BW and SN no disclosure. CS and MD are employees of IB Lab.

Abstract

Purpose

Assessing knee osteoarthritis (OA) is predominantly done radiographically via the Kellgren-Lawrence score (KLS).

Artificial Intelligence (AI) aid during analyzing xrays has been shown to lead to more accurate KL diagnostics and thus improved prognostic values of x-rays.

However, it is unclear wheter those AI-aided diagnostic results more likely correlate with clinical and biomechanical scores.

The aims of this study are to investigate (i) a correlation of clinical scores (KOOS, IPAQ) and (ii) biomechanical values in comparison of the AI-aided versus the AI-unaided x-ray diagnostics.

Subjects were sub-analyzed from a larger, physiotherapy trial (MLKOA).

Methods and Materials

63 patients were analyzed in this study (MLKOA) with symptomatic knee OA ranging from KL0-3.

At baseline x-rays and clinical scores (KOOS, IPAQ) as well as biomechanical values were taken.

X-ray readings at baseline were performed twice by experienced physicians (2 orthopedic surgeons and a radiologist) AI-unaided and again after 3 weeks AI-aided.

Aided and un-aided readings have been performed twice by each reader to minimize intra-reader variability. The order of x-rays was randomly assigned at each reading.

Read subscores in a semi-quantitaive manner included deformity, joint space narrowing, osteophytosis and sclerosis resulting in a numerical value that defines the KL score.

Outcome measures included: ICC = (intra-class correlation/agreement rate in between readers with/without AI); accuracy (surgeons versus ground truth oft he radiologist), Receiver operating Curve (individual learning curve with/without AI) and the correlation with clinical scores.

AI analysis was performed with a software from „Imaging Biopsy Lab“ (Vienna, Austria).

Results

In total 63 x-rays were included after analyzing 72 DICOM pictures (only knees included into MLKOA were analyzed even tough some subjects received an x-ray oft he contralateral knee).

A trend of an increased correlation with AI-aid and clinical scores was detected.

Conclusion

The use of AI in digital imaging analysis increases reproducability and accuracy in diagnosing Osteoarthritis

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Presenter Of 1 Presentation

Osteoarthritis

P153 - Artificial Intelligence in Radiographic Diagnostics in Correlation with Clinical Scores in Knee Osteoarthritis Patients

Abstract

Purpose

Assessing knee osteoarthritis (OA) is predominantly done radiographically via the Kellgren-Lawrence score (KLS).

Artificial Intelligence (AI) aid during analyzing xrays has been shown to lead to more accurate KL diagnostics and thus improved prognostic values of x-rays.

However, it is unclear wheter those AI-aided diagnostic results more likely correlate with clinical and biomechanical scores.

The aims of this study are to investigate (i) a correlation of clinical scores (KOOS, IPAQ) and (ii) biomechanical values in comparison of the AI-aided versus the AI-unaided x-ray diagnostics.

Subjects were sub-analyzed from a larger, physiotherapy trial (MLKOA).

Methods and Materials

63 patients were analyzed in this study (MLKOA) with symptomatic knee OA ranging from KL0-3.

At baseline x-rays and clinical scores (KOOS, IPAQ) as well as biomechanical values were taken.

X-ray readings at baseline were performed twice by experienced physicians (2 orthopedic surgeons and a radiologist) AI-unaided and again after 3 weeks AI-aided.

Aided and un-aided readings have been performed twice by each reader to minimize intra-reader variability. The order of x-rays was randomly assigned at each reading.

Read subscores in a semi-quantitaive manner included deformity, joint space narrowing, osteophytosis and sclerosis resulting in a numerical value that defines the KL score.

Outcome measures included: ICC = (intra-class correlation/agreement rate in between readers with/without AI); accuracy (surgeons versus ground truth oft he radiologist), Receiver operating Curve (individual learning curve with/without AI) and the correlation with clinical scores.

AI analysis was performed with a software from „Imaging Biopsy Lab“ (Vienna, Austria).

Results

In total 63 x-rays were included after analyzing 72 DICOM pictures (only knees included into MLKOA were analyzed even tough some subjects received an x-ray oft he contralateral knee).

A trend of an increased correlation with AI-aid and clinical scores was detected.

Conclusion

The use of AI in digital imaging analysis increases reproducability and accuracy in diagnosing Osteoarthritis

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