The global pandemic has amplified crises such as domestic abuse, limited access to medical care for marginalized communities, and violence against women. In response, global conferences are directing attention towards these pressing issues, advocating for systemic change, and facilitating initiatives and policies that channel commitments into action. At this year’s ICCA Congress we will honour three such associations which have influenced systemic change through their meetings. Join us in recognizing the European AIDS Clinical Society, The Garden of Hope Foundation, and Women Deliver – the 2021 Incredible Impacts winners!