Presenter of 1 Presentation
A NOVEL ULTRAFAST TRANSPARENT ONLINE FLASH MONITOR AND DOSIMETER
Abstract
Background and Aims
We are developing a novel technology for precise, real-time beam monitoring (e.g., X-ray photons, electrons, protons, helium-ions, carbon-ions, etc.) for all modalities of FLASH radiotherapy (FLASH-RT) based on a recently patented, transparent, large-area beam imaging detector. The technology provides beam profiling and dose-rate verification during delivery to ensure patient safety and a beam termination signal if necessary.
Methods
Our FLASH-RT monitor is based on a new, highly efficient, semi/micro-crystalline scintillator film surrounded by an ultrafast, multi-camera machine vision system operating at ≥10,000 frames/second, that continuously streams and analyzes each image during treatment. The system incorporates an innovative folded-optical system with an active scintillator area of 26 x 30 cm. It features a thin profile, rapid internal calibration, and analyzes images every 100 µs for beam position, profile, and dosimetry.
Results
A proof-of-concept was first demonstrated in 2019 with funding from the National Cancer Institute and DOE Office of Science and Office of Nuclear Physics. True 2D-position and beam profile spatial resolutions of <10 µm have been achieved. Besides FLASH-RT, the system with modifications can be adapted for hypofractionated-RT, spatially-fractionated-RT, and BNCT real-time dosimetry and monitoring. It can also monitor and analyze sporadic dose-rate spikes of <100 µs from synchrotron accelerators for proton and carbon-ion therapy. The new scintillator material is highly radiation hard, as demonstrated after 400,000 Gy at dose-rates of ≥3,000 Gy/s.
Conclusions
The described system provides a large-area, precise, ultrafast beam profile analysis and dosimetry system with real-time verification within 100 µs. It is a FLASH-RT-enabling technology.
Author Of 1 Presentation
A NOVEL ULTRAFAST TRANSPARENT ONLINE FLASH MONITOR AND DOSIMETER
Abstract
Background and Aims
We are developing a novel technology for precise, real-time beam monitoring (e.g., X-ray photons, electrons, protons, helium-ions, carbon-ions, etc.) for all modalities of FLASH radiotherapy (FLASH-RT) based on a recently patented, transparent, large-area beam imaging detector. The technology provides beam profiling and dose-rate verification during delivery to ensure patient safety and a beam termination signal if necessary.
Methods
Our FLASH-RT monitor is based on a new, highly efficient, semi/micro-crystalline scintillator film surrounded by an ultrafast, multi-camera machine vision system operating at ≥10,000 frames/second, that continuously streams and analyzes each image during treatment. The system incorporates an innovative folded-optical system with an active scintillator area of 26 x 30 cm. It features a thin profile, rapid internal calibration, and analyzes images every 100 µs for beam position, profile, and dosimetry.
Results
A proof-of-concept was first demonstrated in 2019 with funding from the National Cancer Institute and DOE Office of Science and Office of Nuclear Physics. True 2D-position and beam profile spatial resolutions of <10 µm have been achieved. Besides FLASH-RT, the system with modifications can be adapted for hypofractionated-RT, spatially-fractionated-RT, and BNCT real-time dosimetry and monitoring. It can also monitor and analyze sporadic dose-rate spikes of <100 µs from synchrotron accelerators for proton and carbon-ion therapy. The new scintillator material is highly radiation hard, as demonstrated after 400,000 Gy at dose-rates of ≥3,000 Gy/s.
Conclusions
The described system provides a large-area, precise, ultrafast beam profile analysis and dosimetry system with real-time verification within 100 µs. It is a FLASH-RT-enabling technology.