Author Of 1 Presentation
EFFECTIVE CONTROL OF ENDEMIC CARBAPENEM-RESISTANT ACINETOBACTER BAUMANNII IN A PEDIATRIC INTENSIVE CARE UNIT
Abstract
Background
Acinetobacter baumannii and its antimicrobial resistance are serious emerging problem that cause high morbidity and mortality in critically ill patients.
Objectives
In our pediatric intensive care, an endemic situation with a single specific strain of carbapenem-resistant Acinetobacter baumannii (CRAB) occurred, and we investigated the effectiveness of comprehensive intensified infection control measures for controlling endemic CRAB.
Methods
The study period was divided into three periods, from the month of introduction of the single strain of CRAB to the implementation of the intervention (Period 1; Jun 2017 to Feb 2018), from the implementation until the end of the CRAB spread (Period 2; Mar to Aug 2018), and a follow-up phase (Sep to Dec 2018) of four months. A comprehensive intensified infection control strategy was implemented to prevent the new colonization of CRAB by a multidisciplinary team. All patients, as well as CRAB colonized patients, were isolated. And the strategy focused on environmental cleaning, disinfection enforcement, hand hygiene promotion through PICU staff education, and active surveillance.
Results
The incidence density rate of CRAB, defined as the number of new colonizations or infections per 1,000 patient-days, decreased from 9.10 ± 6.46 (median, 10.56; range, 0 to 18.09) to 5.76 ± 4.00 (median, 4.48; range, 0 to 11.68) after the interventions were implemented. No CRAB colonization or infection occurred during the 4-month follow-up period.
Conclusion
Comprehensive infection control measures effectively controlled endemic CRAB in our PICU. Universal contact precaution and environmental disinfection were crucial in controlling the horizontal spread of CRAB.