Hospital da Luz Lisboa
Anestesiologia

Author Of 1 Presentation

PAEDIATRIC NEUROVASCULAR MALFORMATIONS IN INTENSIVE CARE: REPORT OF 44 CASES

Abstract

Background

Ruptured vascular malformations are the most common cause of intracerebral haemorrhage in children, causing significant morbidity and mortality.

Objectives

To describe the therapeutic approach and neurological outcome in patients admitted to a paediatric intensive care unit (PICU) with arteriovenous malformations (AVMs) and cerebral aneurysms (CAs).

Methods

Retrospective chart review of patients admitted to PICU with AVMs and CAs between January 2008 and December 2018. Neurologic outcome was assessed using King’s Outcome Scale for Childhood Head Injury (KOSCHI), considering good recovery KOSCHI 4-5; vegetative/ severe disability KOSCHI 2-3.

Results

28 cases of AVMs (64%) and 16 CAs (36%) were included: mean age 8.9 years (+/-5.1). Brain CT scan showed subarachnoid hemorrhage in 63% of CAs and parenchymatous haemorrhage in 64% of AVMs. All patients had neurocritical care, fifty-percent of patients underwent neurosurgery and 23% neuroradiological intervention. Seizures were more common in the AVM group (29 vs 6%), unlike vasospasm (11 vs 25%). Rebleeding rate was similar between groups (18 vs 19%), but occurred earlier and with higher mortality in CAs (2/3 within 48h of admission, both died) than AVMs (5/5 after the first week, one died). Another patient died, from ruptured CA (brain death on admission). On transfer from PICU, incidence of neurologic sequelae was similar (57% in AVMs vs 50% in CAs group). At present time: 75% of AVMs vs 69% of ACs show good recovery; 39% of AVMs vs 6,25% of CAs have severe disability.

Conclusion

Early rebleeding had a dismal outcome in our series, justifying a prompt intervention in cases of CAs.

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PAEDIATRIC NEUROVASCULAR MALFORMATIONS IN INTENSIVE CARE: REPORT OF 44 CASES

Abstract

Background

Ruptured vascular malformations are the most common cause of intracerebral haemorrhage in children, causing significant morbidity and mortality.

Objectives

To describe the therapeutic approach and neurological outcome in patients admitted to a paediatric intensive care unit (PICU) with arteriovenous malformations (AVMs) and cerebral aneurysms (CAs).

Methods

Retrospective chart review of patients admitted to PICU with AVMs and CAs between January 2008 and December 2018. Neurologic outcome was assessed using King’s Outcome Scale for Childhood Head Injury (KOSCHI), considering good recovery KOSCHI 4-5; vegetative/ severe disability KOSCHI 2-3.

Results

28 cases of AVMs (64%) and 16 CAs (36%) were included: mean age 8.9 years (+/-5.1). Brain CT scan showed subarachnoid hemorrhage in 63% of CAs and parenchymatous haemorrhage in 64% of AVMs. All patients had neurocritical care, fifty-percent of patients underwent neurosurgery and 23% neuroradiological intervention. Seizures were more common in the AVM group (29 vs 6%), unlike vasospasm (11 vs 25%). Rebleeding rate was similar between groups (18 vs 19%), but occurred earlier and with higher mortality in CAs (2/3 within 48h of admission, both died) than AVMs (5/5 after the first week, one died). Another patient died, from ruptured CA (brain death on admission). On transfer from PICU, incidence of neurologic sequelae was similar (57% in AVMs vs 50% in CAs group). At present time: 75% of AVMs vs 69% of ACs show good recovery; 39% of AVMs vs 6,25% of CAs have severe disability.

Conclusion

Early rebleeding had a dismal outcome in our series, justifying a prompt intervention in cases of CAs.

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