Author Of 1 Presentation
CHANGES IN MORTALITY AMONG EXTREMELY PRETERM INFANTS IN THE SOUTH OF THAILAND: 15-YEAR EXPERIENCE
Abstract
Background
It remains unclear whether after changing in neonatal care over the last few decades, there has been a significant reduction in mortality and morbidity for vulnerable extremely preterm infants (EPT) (gestational age, GA <29 weeks).
Objectives
To evaluate predischarge neonatal mortality, morbidity and associated risk factors in a-15-year experience EPT infants in Songklanagarind hospital.
Methods
Retrospective cohort study of EPT infants GA < 29 week who were born and admitted in neonatal intensive care unit between January 2001 to December 2015. The study was divided into two birth year periods, from 2001-2009 and 2010-2015, the mortality rate by GA were compared by survival analysis with Kaplan-Meier method with statistically significant when p-value < 0.05.
Results
A total of133 EPT infants were enrolled. Seventy-eight infants (58%) were female. The mortality rate was 49/133 (36.8%) and was significantly higher in lower GA infants. (p-value < 0.05). The mortality rate between 2004-2009 and 2010-2015 decreased from 44% to 32.5% but was not statistically significant (p-value = 0.253). The most common cause of death in first period was respiratory distress syndrome (41%) but in the second period, neonatal sepsis (46%) was the common cause of death. Multivariate analysis showed perinatal risk factors of mortality rate were lower GA and birth weight less than 750 grams (OR= 6.8 , 95%CI 0.9,0.9, p-value = 0.001).
Conclusion
Although there was no significant trend in neonatal survival or composite morbidity over the decade but improving in survival were demonstrated with increasing GA and birth weight more than 750 grams.
Presenter of 1 Presentation
CHANGES IN MORTALITY AMONG EXTREMELY PRETERM INFANTS IN THE SOUTH OF THAILAND: 15-YEAR EXPERIENCE
Abstract
Background
It remains unclear whether after changing in neonatal care over the last few decades, there has been a significant reduction in mortality and morbidity for vulnerable extremely preterm infants (EPT) (gestational age, GA <29 weeks).
Objectives
To evaluate predischarge neonatal mortality, morbidity and associated risk factors in a-15-year experience EPT infants in Songklanagarind hospital.
Methods
Retrospective cohort study of EPT infants GA < 29 week who were born and admitted in neonatal intensive care unit between January 2001 to December 2015. The study was divided into two birth year periods, from 2001-2009 and 2010-2015, the mortality rate by GA were compared by survival analysis with Kaplan-Meier method with statistically significant when p-value < 0.05.
Results
A total of133 EPT infants were enrolled. Seventy-eight infants (58%) were female. The mortality rate was 49/133 (36.8%) and was significantly higher in lower GA infants. (p-value < 0.05). The mortality rate between 2004-2009 and 2010-2015 decreased from 44% to 32.5% but was not statistically significant (p-value = 0.253). The most common cause of death in first period was respiratory distress syndrome (41%) but in the second period, neonatal sepsis (46%) was the common cause of death. Multivariate analysis showed perinatal risk factors of mortality rate were lower GA and birth weight less than 750 grams (OR= 6.8 , 95%CI 0.9,0.9, p-value = 0.001).
Conclusion
Although there was no significant trend in neonatal survival or composite morbidity over the decade but improving in survival were demonstrated with increasing GA and birth weight more than 750 grams.