Author Of 1 Presentation
XENON AS COMPONENT OF COMPLEX THERAPY OF POLYTRAUMA IN CHILDREN
Abstract
Background
Xenon (Xe) is a noble gas with anesthetic, analgesic, antistress and other characteristics. Data of therapeutic use in adult allow to predict positive effects in children with polytrauma.
Objectives
Estimate therapeutic effects of Xe in complex therapy of children with polytrauma.
Methods
We studied 7children 16 ± 1,5 years with polytrauma, ISS 30± 5. All suffered from chronic pain and insomnia. In addition to complex treatment Xe inhalations were assigned (Хе :О2 = 20 – 30% : 50 – 30%), duration 15 – 20 min, 3 – 12 times. Xe console КТК - 01 (ООО «КсеМед», Russia), monitor - МР 60 (Philips, USA). We used Visual Analogue Scale (VAS), Ramsay scale, BIS index, cerebral oxygenation indicator to estimate an effect.
Results
The level of pain decreased (VAS) (4,1 ± 1,8 to 1,1 ± 0,4), after session 1,9 ± 1,1 (р< 0,05). The depth of sedation (BIS-index) decline from 95,5 ± 2,5 to 86 ± 5,0, then recovered 93,0 ± 2,1; Ramsay scale from 9,4 ± 0,5 to 2,7 ± 1,2, after grew to 3,7 ± 1,9 (р< 0,05). Cerebral oxygenation increased by 10% during inhalation. Tissue perfusion index rose (р< 0,05) (before 1,5 ± 0,5; during 3,2 ± 1,3; after 2,2 ± 1,0). After 2 - 3 sessions all children’s felt better, slept well without nightmares. Pain relieved after 5-12 sessions.
Conclusion
Xe inhalation improved pain management and stress treatment in pediatric patients in acute period of polytrauma.