Pramukhswami Medical College
Pediatrics
Head, Department of Pediatrics, Pramukhswami Medical College, Karamsad Associate Dean, Research Services, Charutar Arogya Mandal, Karamsad National Joint Coordinator - Advanced IAP NNF NRP Program Ex-Member, Governing Body, National Neonatology Forum, New Delhi Ex-President - National Neonatology Forum Gujarat State Chapter Department of Pediatrics, Pramukhswami Medical College, Karamsad, Anand, Gujarat. Pin-388325 Ph(02692)223868 Mobile: +919825087842 https://www.ncbi.nlm.nih.gov/sites/myncbi/1z7I5oGJZFjkJ/collections/50470789/public/

Author Of 3 Presentations

IS SKIN TO SKIN CARE GIVEN BY FATHER AS EFFECTIVE AS THAT GIVEN BY MOTHER FOR NEONATAL PAIN REDUCTION: A RANDOMIZED CONTROL CROSSOVER TRIAL

Abstract

Background

Skin to skin care (SSC) by mothers has been shown to be effective in providing pain relief. Often mother is not available to provide SSC and father provides it.

Objectives

To compare the pain control efficacy of skin to skin care given by mother and father by premature infant pain profile (PIPP) scale.

Methods

RCT involving stable preterm neonates (30 to 36 wk GA at birth) requiring heel-stick sampling. Study participants were randomly assigned in two groups. For participants in the group A, mother gave SSC starting 10 min prior to the procedure on 1 heel-stick and father gave SSC starting 10 min prior to the procedure on 2 heel-stick. For participants in the group B, father gave SSC on 1 heel-stick and mother gave SSC on 2 heel-stick. Analysis was done by descriptive statistics, independent sample t test and ANOVA.

Results

The study involved a total of 40 neonates. The mean (SD) BW,GA of neonates was 1600(351.7)gm and 34.15(2.3)wk. The mean(SD)PIPP scores for mother SSC group at 0,1,5 min were 3.2(1.2),7.7(4.2),3.7(1.5) respectively and in father SSC group, values at 0,1.5 min were 3.1(1.3),8.6(4.3),4.2(2.3) respectively. The difference between the PIPP score between the two groups was not significant (P values were 0.79 (0 min), 0.35(1 min) and 0.31(5 min)).

boxplotanal.jpg

Conclusion

Pain reduction with skin to skin care by father is not significantly different as compared to that by mother. The trend of lower pain scores in skin to skin care by mother group will be further explored by a larger follow up trial.

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RANDOMISED CONTROL TRIAL OF FOOT OPERATED RESUSCITATOR VERSUS ROUTINE BAG AND MASK FOR NEONATAL RESUSCITATION AT BIRTH

Abstract

Background

Foot operated newborn resuscitator (FOR) has been developed with intention of improving the ease with which newborn resuscitation can be carried out in neonates requiring positive pressure ventilation (PPV).

Objectives

The primary outcome was to determine the non-inferiority of foot operated resuscitator versus routine bag and mask ventilation (BMV) in increasing heart rate above 100/min after 30 seconds of PPV.

Methods

Study conducted in a teaching hospital providing tertiary level care for neonates. Neonates around 35 weeks gestation requiring newborn resuscitation and meeting pre-existing criteria for requirement of Bag and Mask ventilation were included in the study. Sample size was 60 neonates was needed to detect a mean difference of 1.78 with 80% power. Analysis was by intention to treat.

Results

60 cases were enrolled (31 in FOR; 29 in BMV). Foetal distress, HR>100 at 30/60 sec, neonate intubation, NICU admission and survival were similar in both groups (Chi square test). Mean (SD) time to establish spontaneous breathing in FOR [61.2(36.5)] was lower as compared to to BMV [114(126)]. (p value = 0.054). Median(IQR) time to establish spontaneous breathing FOR [60(30)] vs BMV [60(75)] was not different. The median(IQR) duration of noninvasive ventilation in seconds for FOR (60(30)) and Bag and Mask group (60(105))was comparable(p = 0.465). Variation in time taken is high in BMV suggesting that the FOR device is easier to operate by health personnel.forimage.jpg

Conclusion

Foot operated resuscitator is as good as, if not better in providing positive pressure ventilation in neonates.

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SKIN TO SKIN CARE VERSUS SUCROSE AS A PAIN CONTROL INTERVENTION FOR PREMATURE NEONATES: A BLINDED RANDOMIZED CONTROL CROSSOVER TRIAL

Abstract

Background

Skin to skin care (SSC) and sucrose, both have been shown to be effective in providing pain relief for premature neonates. There is lack of strong evidence for choosing one over other because of limited comparison data

Objectives

To compare the effect of SSC and oral Sucrose on pain control of preterm neonates by premature infant pain profile (PIPP) scale.

Methods

This is an crossover RCT involving stable preterm neonates (28 - 36 wk GA at birth) conducted during Jan- Dec 2018. In group A, SSC was started 10 min before 1 heel-stick, SSC was continued post procedure as per the unit protocol and 0.2 ml 24% oral sucrose was given 2 min before the 2 heelstick. In group B, 0.2 ml 24% oral sucrose was given 2 min before the 1 heel-stick and SSC was started 10 min before 2 heel-stick.

Results

The study involved 100 neonates (45 female, 55 male). The mean (SD) total PIPP score at baseline was significantly lower in sucrose group [2.75(1.36) vs 3.4(1.01), p<0.001]. The mean (sd) total PIPP score at 5 min is significantly lower in the sucrose group than KMC group [3.1(1.27) vs 3.5(1.19) p<0.01]. This difference in sucrose group attribute to behavioural state of the neonate [2.1(1.09) vs 2.5(0.8) p<0.01] and brow bulge (facial expression) of neonate [0.05(0.2) vs 0.09(0.4) p<0.05].

boxplotsucvskmc.jpg

Conclusion

SSC and oral sucrose have comparable efficacy in reducing premature neonatal pain. Given that SSC offers several additional bshould be the first preference for providing pain control in preterm neonates whenever possible.

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Presenter of 3 Presentations

IS SKIN TO SKIN CARE GIVEN BY FATHER AS EFFECTIVE AS THAT GIVEN BY MOTHER FOR NEONATAL PAIN REDUCTION: A RANDOMIZED CONTROL CROSSOVER TRIAL

Abstract

Background

Skin to skin care (SSC) by mothers has been shown to be effective in providing pain relief. Often mother is not available to provide SSC and father provides it.

Objectives

To compare the pain control efficacy of skin to skin care given by mother and father by premature infant pain profile (PIPP) scale.

Methods

RCT involving stable preterm neonates (30 to 36 wk GA at birth) requiring heel-stick sampling. Study participants were randomly assigned in two groups. For participants in the group A, mother gave SSC starting 10 min prior to the procedure on 1 heel-stick and father gave SSC starting 10 min prior to the procedure on 2 heel-stick. For participants in the group B, father gave SSC on 1 heel-stick and mother gave SSC on 2 heel-stick. Analysis was done by descriptive statistics, independent sample t test and ANOVA.

Results

The study involved a total of 40 neonates. The mean (SD) BW,GA of neonates was 1600(351.7)gm and 34.15(2.3)wk. The mean(SD)PIPP scores for mother SSC group at 0,1,5 min were 3.2(1.2),7.7(4.2),3.7(1.5) respectively and in father SSC group, values at 0,1.5 min were 3.1(1.3),8.6(4.3),4.2(2.3) respectively. The difference between the PIPP score between the two groups was not significant (P values were 0.79 (0 min), 0.35(1 min) and 0.31(5 min)).

boxplotanal.jpg

Conclusion

Pain reduction with skin to skin care by father is not significantly different as compared to that by mother. The trend of lower pain scores in skin to skin care by mother group will be further explored by a larger follow up trial.

Hide

RANDOMISED CONTROL TRIAL OF FOOT OPERATED RESUSCITATOR VERSUS ROUTINE BAG AND MASK FOR NEONATAL RESUSCITATION AT BIRTH

Abstract

Background

Foot operated newborn resuscitator (FOR) has been developed with intention of improving the ease with which newborn resuscitation can be carried out in neonates requiring positive pressure ventilation (PPV).

Objectives

The primary outcome was to determine the non-inferiority of foot operated resuscitator versus routine bag and mask ventilation (BMV) in increasing heart rate above 100/min after 30 seconds of PPV.

Methods

Study conducted in a teaching hospital providing tertiary level care for neonates. Neonates around 35 weeks gestation requiring newborn resuscitation and meeting pre-existing criteria for requirement of Bag and Mask ventilation were included in the study. Sample size was 60 neonates was needed to detect a mean difference of 1.78 with 80% power. Analysis was by intention to treat.

Results

60 cases were enrolled (31 in FOR; 29 in BMV). Foetal distress, HR>100 at 30/60 sec, neonate intubation, NICU admission and survival were similar in both groups (Chi square test). Mean (SD) time to establish spontaneous breathing in FOR [61.2(36.5)] was lower as compared to to BMV [114(126)]. (p value = 0.054). Median(IQR) time to establish spontaneous breathing FOR [60(30)] vs BMV [60(75)] was not different. The median(IQR) duration of noninvasive ventilation in seconds for FOR (60(30)) and Bag and Mask group (60(105))was comparable(p = 0.465). Variation in time taken is high in BMV suggesting that the FOR device is easier to operate by health personnel.forimage.jpg

Conclusion

Foot operated resuscitator is as good as, if not better in providing positive pressure ventilation in neonates.

Hide

SKIN TO SKIN CARE VERSUS SUCROSE AS A PAIN CONTROL INTERVENTION FOR PREMATURE NEONATES: A BLINDED RANDOMIZED CONTROL CROSSOVER TRIAL

Abstract

Background

Skin to skin care (SSC) and sucrose, both have been shown to be effective in providing pain relief for premature neonates. There is lack of strong evidence for choosing one over other because of limited comparison data

Objectives

To compare the effect of SSC and oral Sucrose on pain control of preterm neonates by premature infant pain profile (PIPP) scale.

Methods

This is an crossover RCT involving stable preterm neonates (28 - 36 wk GA at birth) conducted during Jan- Dec 2018. In group A, SSC was started 10 min before 1 heel-stick, SSC was continued post procedure as per the unit protocol and 0.2 ml 24% oral sucrose was given 2 min before the 2 heelstick. In group B, 0.2 ml 24% oral sucrose was given 2 min before the 1 heel-stick and SSC was started 10 min before 2 heel-stick.

Results

The study involved 100 neonates (45 female, 55 male). The mean (SD) total PIPP score at baseline was significantly lower in sucrose group [2.75(1.36) vs 3.4(1.01), p<0.001]. The mean (sd) total PIPP score at 5 min is significantly lower in the sucrose group than KMC group [3.1(1.27) vs 3.5(1.19) p<0.01]. This difference in sucrose group attribute to behavioural state of the neonate [2.1(1.09) vs 2.5(0.8) p<0.01] and brow bulge (facial expression) of neonate [0.05(0.2) vs 0.09(0.4) p<0.05].

boxplotsucvskmc.jpg

Conclusion

SSC and oral sucrose have comparable efficacy in reducing premature neonatal pain. Given that SSC offers several additional bshould be the first preference for providing pain control in preterm neonates whenever possible.

Hide