Author Of 1 Presentation
CLINICAL AND MICROBIOLOGICAL STUDY OF BACTERAEMIA IN PICU PATIENTS (2013-2017)
Abstract
Background
Bacteraemias are responsible for increased morbidity, mortality, prolonged length of stay in PICU patients.
Objectives
Study of microbiological and epidemiological characteristics of bacteraemia occurring in PICU patients.
Methods
All septicaemias with positive blood cultures (BACTEK 9240) were included. Microbiological and epidemiological data were retrieved retrospectively, based on LIS of Microbiology Department and PICU medical files.
Results
From 2013 to 2017, 1181 patients were admitted. 93 bacteraemia incidents were documented in 67 patients (57% boys, age: 18 days-16 years old). Two strains were isolated in 9 incidents whereas, 16 patients had multiple episodes of bacteraemia (in 10 patients: 2 episodes, in 4 patients: 3 episodes, in 2 patients: 4 episodes). Total length of stay was 1-192 days (median: 33 days), hospitalization days in PICU prior to bacteraemia were 3-120 days (median: 13 days), duration of septicemia was 1-9 days (median: 1 day). In total, 102 strains were isolated: 53 Gram(-) bacteria (Enterobacterspp: 16, Klebsiellaspp: 10, P.aeruginosa: 9, A.baumanii: 5, S.maltophiliα: 5, E.coli: 4, N.meningitidis: 1, E.meningosepticum: 1, S.marcescens: 1, Campylobacter jejuni: 1) and 49 Gram(+) bacteria (staphylococci coagulase negative: 31, S.aureus: 9, Enterococcusspp: 5, Candida albicans: 2, Bacillusspp: 2). Only three strains were carbapenemases producers (A.baumanii, P.aeruginosa, K.pneumoniae) and 2 strains (E.cloacae) were ESBL(+)/cephalosporinases overproducers. In total, 75 incidents of bacteraemia were categorized as nosocomial infections (13.7/1000 hospitalization days).
Conclusion
Multiresistant strains were rarely isolated in our unit. No epidemic was detected, however constant vigilance is required to assure firm compliance to infection control measures.