EP448 - COVID-19 IN ADMITTED PEDIATRIC PATIENTS – HOW TO SCREEN? (ID 481)
- Giuliana Pucarelli (Brazil)
- Marianna Venceslau (Brazil)
- Thalita Abreu (Brazil)
- Ana cristina Frota (Brazil)
- Maria Angelica Guimaraes (Brazil)
- Fernanda Queiroz (Brazil)
- Thiago Anchoreta (Brazil)
- Catherine Cordeiro (Brazil)
- Terezinha marta Castineiras (Brazil)
- Regina Rocha (Brazil)
- Cristina B. Hofer (Brazil)
Abstract
Backgrounds:
The diagnosis of COVID-19 in the pediatric population still poses a challenge but nevertheless it is necessary when admitting a patient to avoid possible nosocomial outbreaks. Since a screening test at admission is not always available, and in most lower income countries, the pediatric wards do not have private rooms, a screening tool, considering history and basic laboratory tests must be pursuit. In this study we aimed to compare the epidemiological/clinical/laboratory manifestations between children who tested positive and negative for SARS-CoV-2.
Methods
cohort study, with children admitted to the hospital with diagnosis of upper-airway infection, pneumonia, bronchiolitis, fever with rash, diarrhea, or encephalitis which were tested with nasopharyngeal swab for qRT-PCR for COVID-19. We compared clinical and laboratorial manifestations between children COVID-19 positive and negative using logistic regression.
Results:
A total of 533 patients were recruited from April 14, 2020 to April 30, 2021. The median age was 44 months (ranging from 1 to 192), 286 were male (55%), 329 (65%) had previous comorbidities and 31 (15%) use immunosuppressive drugs. 105 (20%) were COVID positive, In the multivariate analysis older children (OR=1.08 – 95%CI= 1.02-1.14), with lower white blood cells at admission (OR=0.98 – 95%CI= 0,98-1.00), and whose domiciliary contact is suspect to have COVID-19 (OR=1,60 – 95%CI= 1,02-2,60), presented higher chance to be infected with SARS-COV-2.
Conclusions/Learning Points:
The epidemiological history of domiciliary contact with suspected COVID-19 infected member should be used in the case definition with other clinical variables when the PCR/antigen test results are not promptly available at patient admission, as a screening tool for SARS-COV-2.
