AS11. Diagnostics and biomarkers

EP352 - GASTROINTESTINAL PANEL PERFORMANCE FOR THE DIAGNOSIS OF ACUTE GASTROENTERITIS IN PEDIATRIC PATIENTS (ID 1194)

Abstract

Backgrounds:

A variety of methods are used for identification of acute gastroenteritis (AGE) causative organisms. Gastrointestinalpanel (GI-P) has the potential to detect up to 22 pathogens rapidly. We focused on the clinical impact of GI-P on the pediatric population

Methods

A Retrospective study conducting GI-Ps and clinical details of inpatient pediatric patients presenting with AGE in a tertiary hospital over one year.

Results:

220 GI-P samples were collected. 154 (70%) samples were positive with at least one organism being mostly detected in toddlers. 35% (78) had single organism while 5% (11) detected 4 or more organisms. The most common bacteria was Enteropathogenic E.coli with peak detection in July and September. Norovirus was detected in 21% followed by Rota virus. Viruses were as well detected mostly in July. Parasites were detected in 7 specimens. GI-P and stool culture were done in 134 sample and were positive with the same organism in 18 specimens versus 3 with a different organism than in stool culture. 96 samples had positive GI-P but negative stool culture, 72 samples had positive GI-P but negative both stool analysis and culture while 40 were clinically sick patients presenting with picture of AGE.

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Conclusions/Learning Points:

GI-P is valuable tool in detecting the causative pathogen of AGE in children specially if clinically sick; although it can detect multiple organisms which might indicate a carrier status. The most commonly detected bacteria was Enteropathogenic E.coli. while Norovirus was the most common virus detected

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