My focus has been to holistically improve the outcome of children with intestinal polyps, specifically hereditary precancerous polyposis syndromes and, by extension, therapeutic endoscopy. I have advocated for a coordinated, multidisciplinary approach to polyposis syndromes, aligned with a robust effort in clinical and translational research. My research and publications span the gamut of specific polyposis recognition, genotype-phenotype correlation, management and outcomes including transition of care. I am involved, as part of the Kansas University Cancer Center, in basic research on the microbiome modulation of polyp to cancer transition, and the proteomic evolution of growing adenomatous polyps. I have been honored to be part of ESPGHAN for over two decades and a member of the Polyposis Working Group. Relatedly, in 2020 I founded, and now chair the Polyposis Special Interest Group in NASPGHAN and have created a collaboration with LASPGHAN. I chair the organizing committee for the first ever Single Topic Symposium on Pediatric Polyposis during the NASPGHAN Annual Meeting (2023). My goal is to improve the care of this vulnerable group of patients, understanding and mitigating their disease expression. This can only be accomplished through broad collaboration between societies, other subspecialities and aggressive support of our younger colleagues in this field.