Hopital Beaujon ICU
Hopital Beaujon
ICU

Author of 1 Presentation

Pancreas Diffuse Disease Poster presentation - Scientific

SE-127 - Quantification of pancreas surface lobularity on CT: a feasibility study in the normal pancreas

Abstract

Purpose

To assess the feasibility and reproducibility of pancreatic surface lobularity (PSL) quantification derived from abdominal CT in a population of patients free of pancreatic disease.

Material and methods

Retrospective study including patients free of pancreatic diseases who underwent contrast-enhanced abdominal CT between 2017 and 2019. PSL was independently measured by two abdominal radiologists on the anterior side of the head/isthmus (5 measures/patient), body and tail (3 measures/patient each) of the pancreas, using a dedicated software. PSL was considered reliable when at least 5 measurements were obtained. Inter-reader agreement was assessed by the intraclass correlation coefficient (ICC) and Bland Altman (BA) plots.

Results

164 patients (142 men [87%], mean 45 yr [18–91]) were included. A total of 1488/1804 (82%) measurements were reliable. The median number of measurements/patient was 10 (range 1-11). A total of 152/164 patients had at least five reliable measurements (PSL success rate 93%). The mean PSL was 6.68±1.58, 6.34±1.64 and 7.77±1.93 in the head/isthmus, body and tail, respectively (p<0.001). After patient stratification by age (18-30 yo [n=42]; 31-50 yo [n=53]; 51-70 yo [n=59], and 71+ yo [n=10]), PSL was shown to gradually increase with age (head: 6.01 to 8.18, body: 6.04 to 6.81; tail: 7.23 to 8.48). Inter-reader agreement was excellent with an ICC of 0.82 (95%CI 0.72-0.85, P<0.001). BA plot showed bias of 0.29 and limits of agreement of -1.66 and 2.55.

Conclusion

CT-based pancreatic surface lobularity quantification is feasible with a high success rate and excellent inter-reader agreement in patients free of pancreatic disease. Our study provides normal references for further studies.

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