The University of Tokyo Hospital Radiology
The University of Tokyo Hospital
Radiology

Author of 1 Presentation

Liver - Focal Liver Lesions Poster presentation - Scientific

SE-075 - EOB-MRI findings useful for the diagnosis of colorectal liver metastases with Glisson’s capsule invasion

Abstract

Purpose

Glisson’s capsule invasion in patients with colorectal liver metastases (CLM) is reported to associate with R1 resection. We aimed to elucidate gadolinium-ethoxybenzyl-diethylenetriamine-enhanced MRI (EOB-MRI) findings of Glisson’s capsule invasion of CLM.

Material and methods

Ten CLM lesions (6 with Glisson’s capsule invasion and 4 without) from 4 consecutive patients (male/female, 3/1; average age, 70.3) who underwent EOB-MRI and CLM resection within 1.5 months interval during the last 2 years were included in this study. Hepatobiliary phase T1-weighted images of EOB-MRI was assessed by a board-certified abdominal radiologist for the presence or absence of geographic and striate hypo-intensity areas adjoining CLM lesions. The association between pathologically proven Glisson’s capsule invasion and EOB-MRI findings were assessed statistically.

Results

In CLM with Glisson’s capsule invasion, frequencies of geographic and striate hypo-intensity areas adjoining CLM on hepatobiliary phase images were 67% (4/6) and 67% (4/6), respectively. In CLM without Glisson’s capsule invasion, they were 25% (1/4) and 25% (1/4), respectively. Presence of either of geographic or striate hypo-intensity areas was a significant predictive finding for Glisson’s capsule invasion (Fisher’s exact test, P = .03) and its sensitivity, specificity, positive predictive value, and negative predictive value were 100%, 75%, 86%, and 100%, respectively.

Conclusion

The presence of either of geographic or striate hypo-intensity areas on hepatobiliary phase images of EOB-MRI could be a useful finding that could predict Glisson’s capsule invasion of CLM.

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