Author of 1 Presentation
SE-030 - Clinical impact of dedicated whole-body MR imaging in patients with advanced colorectal cancer
Abstract
Purpose
To evaluate the clinical impact of dedicated whole-body MRI (WB-MRI) in patients with stage IV colorectal cancer (CRC) on CT.
Material and methods
This was a retrospective study of 42 patients with CRC referred to our specialist oncologic center with suspicion of liver and/or peritoneal metastasis. All patients underwent an additional 3T WB-MRI at our institution, including pre/postcontrast T1, T2 and diffusion weighted imaging (DWI). Multidisciplinary team (MDT) meeting notes were evaluated and if the result of WB-MRI changed the original treatment plan (based on the CT result), it was regarded as a significant clinical impact.
Results
All metastases detected on CT images were also detected with WB-MRI. WB-MRI changed the treatment strategy in 13 patients (31%). WB-MRI diagnosed additional liver and peritoneal metastases in 3 (7%) and 1 (2%) patients, respectively. WB-MRI confirmed or ruled out liver and peritoneal metastases in indeterminate CT studies in 1 (2%) and 6 (14%) patients respectively. In one patient (2%), WB-MRI confirmed pulmonary metastasis in a lesion that was indeterminate with CT and in another patient (2%) WB-MRI detected an additional metastatic lesion in the anterior abdominal wall and potential renal malignancy.
Conclusion
Dedicated WB-MRI changed the treatment plan in almost one third (31%) of patients with stage IV CRC on CT. WB-MRI should be considered in this patient group to prevent undertreatment.