Author of 1 Presentation
SS 14.4 - Mapping of the liver function: impact of MR field strength on T1 reduction rate
Abstract
Purpose
To determine whether T1 reduction rate is dependent on field strength in patients with and without liver cirrhosis.
Material and methods
85 consecutive gadoxetic acid (Gd-EOB-DTPA) liver MRI scans with available T1 mapping pre- and post-contrast administration in the equilibrium phase were analyzed between September 2018 and January 2019. 44 exams were performed on a 1.5T system and 41 exams on a 3T system. Each of these two groups was then divided into patients with and without liver cirrhosis. T1 reduction rates were calculated as (native T1 – post-contrast T1)/native T1. Groups were compared using a Mann-Whitney U test.
Results
At 1.5T 23 patients had cirrhosis, while 21 patients had no cirrhosis. At 3T 17 patients had cirrhosis, while 24 patients had no cirrhosis. At both 3T and 1.5T T1 reduction rate discriminated between patients with and without cirrhosis (p=0.001 and p>0.001). T1 reduction rates did not differ significantly between 3T and 1.5T in patients with cirrhosis (median 60% vs. 59%; p=0.991) and without cirrhosis (median 75% vs. 75%; p=0.787).
Conclusion
This study shows that T1 reduction rate is comparable between 3T and 1.5T and may discriminate patients with and without liver cirrhosis as an imaging surrogate to map liver function.
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Poster Author of 1 e-Poster
SE-061 - Liver vein to cava attenuation (LVCA): a simple parameter to increase predictive value of caudate-right lobe ratio (CRL-R) and liver segmental volume ratio (LSVR) to detect significant liver fibrosis on portal venous phase abdominal CT scans
Author of 1 Presentation
SE-061 - Liver vein to cava attenuation (LVCA): a simple parameter to increase predictive value of caudate-right lobe ratio (CRL-R) and liver segmental volume ratio (LSVR) to detect significant liver fibrosis on portal venous phase abdominal CT scans
Abstract
Purpose
To investigate incremental value of liver vein to cava attenuation (LVCA) in combination with caudate-right lobe ratio (CRL-R) and liver segmental volume ratio (LSVR) to predict significant liver fibrosis on portal venous phase abdominal CT scans.
Material and methods
212 patients were retrospectively included: 107 consecutive patients with liver biopsy and portal venous phase abdominal CT within 6 months and 105 patients without liver fibrosis, based on liver MR elastography (<2.8 kPa). The patients were grouped into patients with clinically significant fibrosis (73 patients with fibrosis grade 2-4 in histology) and patients without clinically significant fibrosis (139 patients, 34 with fibrosis grade 0-1 and 105 patients without liver fibrosis based on MR elastography). CRL-R and LSVR were calculated alone and multiplied with LVCA (1: liver veins hyperdense, 2: isodense, 3: hypodense compared to vena cava, 4: liver veins not contrasted). Resulting scores were called liver imaging morphology and attenuation based fibrosis score (LIMA) and liver segmental volume and attenuation ratio (LSVAR). ROC-analysis was performed.
Results
LVCA-enhanced LIMA fibrosis score and LSVAR (AUC 0.76 and 0.80, p<0.001) performed better than CRL-R and LSVR (AUC 0.72 and 0.76, p<0.001). Simple LIMA fibrosis score showed similar performance than liver volumetry based LSVR, requiring time-consuming image postprocessing.
Conclusion
LIMA fibrosis score, as a combination of LVCA and CRL-R, showed better performance than CRL-R alone and similar performance than time-consuming LSVR. LSVAR, as a combination of LVCA and LSVR was the overall best predictor for significant liver fibrosis.
Author of 1 Presentation
SS 14.4 - Mapping of the liver function: impact of MR field strength on T1 reduction rate (ID 280)
Abstract
Purpose
To determine whether T1 reduction rate is dependent on field strength in patients with and without liver cirrhosis.
Material and methods
85 consecutive gadoxetic acid (Gd-EOB-DTPA) liver MRI scans with available T1 mapping pre- and post-contrast administration in the equilibrium phase were analyzed between September 2018 and January 2019. 44 exams were performed on a 1.5T system and 41 exams on a 3T system. Each of these two groups was then divided into patients with and without liver cirrhosis. T1 reduction rates were calculated as (native T1 – post-contrast T1)/native T1. Groups were compared using a Mann-Whitney U test.
Results
At 1.5T 23 patients had cirrhosis, while 21 patients had no cirrhosis. At 3T 17 patients had cirrhosis, while 24 patients had no cirrhosis. At both 3T and 1.5T T1 reduction rate discriminated between patients with and without cirrhosis (p=0.001 and p>0.001). T1 reduction rates did not differ significantly between 3T and 1.5T in patients with cirrhosis (median 60% vs. 59%; p=0.991) and without cirrhosis (median 75% vs. 75%; p=0.787).
Conclusion
This study shows that T1 reduction rate is comparable between 3T and 1.5T and may discriminate patients with and without liver cirrhosis as an imaging surrogate to map liver function.