Author of 1 Presentation
SS 3.5 - Detection of extrapancreatic perineural invasion in pancreatic head ductal adenocarcinoma: utility of four MDCT patterns of spread (ID 986)
Abstract
Purpose
To determine sensitivity and specificity of four MDCT patterns of perineural spread in pancreatic ductal adenocarcinoma: linear, reticular, mass-like and nodular.
Material and methods
This study included 50 adults (28 men and 22 women, mean age, 66 years; range 44–88 years) with pancreatic head mass who underwent MDCT. Three blinded radiologists independently reviewed each MDCT exam and four patterns of perineural spread were assessed: (1) linear, (2) reticular, (3) mass-like and (4) nodular. Sensitivity, specificity, and positive and negative predictive values of the patterns were calculated, as well as interobserver agreement.
Results
Sensitivity, specificity, and positive and negative predictive values of the “linear” pattern of perineural spread for the three readers were 25–51%, 77–85%, 54–78% and 71–81%, respectively (κ = 0.51); for the “reticular” pattern, they were 48–63%, 82–90%, 56–88%, and 75–78%, respectively (κ = 0.6); for the “mass-like” pattern, they were 52–71%, 85–92%, 64–87%, and 62–68%, respectively (κ = 0.64) and for the “nodular” pattern, they were 21–24%, 66–72%, 52–75%, and 32–35%, respectively (κ = 0.44).
Conclusion
The “reticular” and “mass-like” MDCT patterns have high specificity for detecting extrapancreatic perineural invasion in PDAC.
Presenter of 1 Presentation
SS 3.5 - Detection of extrapancreatic perineural invasion in pancreatic head ductal adenocarcinoma: utility of four MDCT patterns of spread (ID 986)
Abstract
Purpose
To determine sensitivity and specificity of four MDCT patterns of perineural spread in pancreatic ductal adenocarcinoma: linear, reticular, mass-like and nodular.
Material and methods
This study included 50 adults (28 men and 22 women, mean age, 66 years; range 44–88 years) with pancreatic head mass who underwent MDCT. Three blinded radiologists independently reviewed each MDCT exam and four patterns of perineural spread were assessed: (1) linear, (2) reticular, (3) mass-like and (4) nodular. Sensitivity, specificity, and positive and negative predictive values of the patterns were calculated, as well as interobserver agreement.
Results
Sensitivity, specificity, and positive and negative predictive values of the “linear” pattern of perineural spread for the three readers were 25–51%, 77–85%, 54–78% and 71–81%, respectively (κ = 0.51); for the “reticular” pattern, they were 48–63%, 82–90%, 56–88%, and 75–78%, respectively (κ = 0.6); for the “mass-like” pattern, they were 52–71%, 85–92%, 64–87%, and 62–68%, respectively (κ = 0.64) and for the “nodular” pattern, they were 21–24%, 66–72%, 52–75%, and 32–35%, respectively (κ = 0.44).
Conclusion
The “reticular” and “mass-like” MDCT patterns have high specificity for detecting extrapancreatic perineural invasion in PDAC.