Author of 1 Presentation
SS 2.2 - Performance and evaluation in CTC screening: a cluster randomised trial
Abstract
Purpose
To determine if a structured CTC training programme for experienced CTC readers increases interpretation accuracy.
Material and methods
We recruited representative, experienced CTC radiologists (median: 500-999 CTCs interpreted) who interpret CTC in their routine practice (median: 151 to 200 cases/year) from 72 NHS hospitals. We cluster randomised them into intervention (one-day training plus regular feedback) or control (no training or feedback) groups. Participants’ sensitivity for colorectal cancer (CRC) and 6mm+ polyps was tested at 0, 1, 6 and 12 months post-training (intervention group) or post-enrollment date (control group), via interpretation of 10 CTC examinations with endoscopic validation. The primary outcome was the difference in sensitivity for 6mm+ polyps at the 1-month test between arms, analysed using analysis of covariance (ANCOVA). Secondary outcomes include diagnostic sensitivity at 6 and 12 months.
Results
139 radiologists were randomised (intervention: 79; control: 60); currently, data regarding the primary outcome are available for 89 (due to ongoing follow-up). Mean baseline sensitivity was similar between the two groups (intervention: 49.7% ±17.4%; control: 45.1% ±13.4%, p=NS). At 1 month post-intervention, sensitivity was significantly greater in the intervention arm than the control group (intervention: 66.3% ±16.8%; control: 46.8% ±19.7%; difference = 16.9% [95%CI 9.9 to 23.8%], p<0.001). This effect persisted at 6 months (intervention: 65.9% ±14.6%; control: 55.3% ±16.5%; difference = 10.0% [95%CI 2.4 to 17.6%], p=0.01).
Conclusion
An easily administered intervention of one-day training with regular ongoing feedback significantly increases experienced CTC radiologist sensitivity for 6mm+ polyps, an effect sustained to at least 6 months.
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Author of 1 Presentation
SS 2.2 - Performance and evaluation in CTC screening: a cluster randomised trial (ID 700)
Abstract
Purpose
To determine if a structured CTC training programme for experienced CTC readers increases interpretation accuracy.
Material and methods
We recruited representative, experienced CTC radiologists (median: 500-999 CTCs interpreted) who interpret CTC in their routine practice (median: 151 to 200 cases/year) from 72 NHS hospitals. We cluster randomised them into intervention (one-day training plus regular feedback) or control (no training or feedback) groups. Participants’ sensitivity for colorectal cancer (CRC) and 6mm+ polyps was tested at 0, 1, 6 and 12 months post-training (intervention group) or post-enrollment date (control group), via interpretation of 10 CTC examinations with endoscopic validation. The primary outcome was the difference in sensitivity for 6mm+ polyps at the 1-month test between arms, analysed using analysis of covariance (ANCOVA). Secondary outcomes include diagnostic sensitivity at 6 and 12 months.
Results
139 radiologists were randomised (intervention: 79; control: 60); currently, data regarding the primary outcome are available for 89 (due to ongoing follow-up). Mean baseline sensitivity was similar between the two groups (intervention: 49.7% ±17.4%; control: 45.1% ±13.4%, p=NS). At 1 month post-intervention, sensitivity was significantly greater in the intervention arm than the control group (intervention: 66.3% ±16.8%; control: 46.8% ±19.7%; difference = 16.9% [95%CI 9.9 to 23.8%], p<0.001). This effect persisted at 6 months (intervention: 65.9% ±14.6%; control: 55.3% ±16.5%; difference = 10.0% [95%CI 2.4 to 17.6%], p=0.01).
Conclusion
An easily administered intervention of one-day training with regular ongoing feedback significantly increases experienced CTC radiologist sensitivity for 6mm+ polyps, an effect sustained to at least 6 months.