Author of 1 Presentation
SE-100 - To quantify graft regeneration and identify factors that impact outcomes in recipients using CT Volumetry post living donor liver transplantation.
Abstract
Purpose
In living donor liver transplantation, graft regeneration is critically dependent on a number of factors. The aim of this study is to use CT Volumtery to calculate volumes of graft post transplantation, quantify graft regeneration and identify factors that impact outcomes in recipients.
Material and methods
A retrospective study of 47 males and 5 females, between 28-54 years of age, living donor transplants, from June 2017 to November 2019, was performed. To detect vascular abnormalities and cause of altered enzymes, 48 out of 52 patients underwent a CT study in post operative period of first 3 months. The study was performed on 128 slice Philips CT scanner.In addition to routine examination, volume of the graft was calculated using the ISP software for liver volume analysis. The cut off of value of 70% of the initial graft volume for a healthy regeneration was considered. Two radiologists reviewed images independently. Factors considered were recipient weight, MELD scoring and platelet counts.
Results
25 out of 48 (52%) recipients showed 70% regeneration in 2nd week.19 out of 48 patients (39.5%) patients in the 3rd week. 4 out of 48 patients (0.08%) had delayed regeneration in the 4th week.5 patients underwent CT in the third week. 11 patients had relatively poor MELD score ,4 patients had higher platelet counts and 3 patients had postoperative complications.The reasons for these variations were studied and enumerated.
Conclusion
CT volumetry analysis helps in assessment, correlation and prediction of factors in the enhancement or limitation of graft regeneration in LDLT.