Author of 1 Presentation
SS 2.3 - CTC post-imaging colorectal cancer rate in a large single-centre retrospective study: using flythrough may reduce the rate of interval cancers (ID 719)
Abstract
Purpose
To determine the rate of CTC post-imaging colorectal cancer (CRC) in a large teaching hospital in the United Kingdom and to examine possible contributing factors in ‘missed’ cancer cases.
Material and methods
All CTCs performed in our centre between January 2014 and September 2016 were retrospectively reviewed. The local cancer registry was used to determine the number of CTC-diagnosed CRCs during the study period, and the number of post-imaging CRCs in 36 months of follow-up.
Results
Over the study period, 4878 CTCs were performed on a total of 4797 patients. CTC detected 173 CRCs. Over 36 months of follow-up, we found 12 post-imaging CRCs. Thus, the post-imaging CRC rate was 6.49 (95% CI 3.40 - 11.10) per 100 cancers, and 2.46 (1.27 - 4.29) per 1000 CTCs. In retrospect, nine lesions were present on the index examination, two had sub-optimal CTC examinations, and one case was not visible on retrospective review. In cases of missed CRC, a) the initial study was not reported using flythrough and b) mean reporting times were significantly lower than the global mean.
Conclusion
We suggest that routine use of virtual flythrough when reporting CTC may reduce the rate of interval colorectal cancers. In sub-optimal studies, the report should be explicit that a repeat examination should be considered.