B. Dachew, Australia

Curtin University School of Public Health
Berihun is an epidemiologist and public health researcher and currently a post-doctoral research fellow at Curtin University, School of Public Health, Perth, Western Australia. He has recently received his PhD from the University of Queensland, Australia. His PhD focuses on pregnancy complications and the risk of mental and behavioural health disorders in offspring using one of the largest longitudinal birth cohort study: the Avon Longitudinal Study of Parents and Children ( ALSPAC). He obtained MPH in Epidemiology and Biostatistics from the University of Gondar and MSc in Adult Health Nursing from Addis Ababa University, Ethiopia. Prior to his PhD study, he had been a faculty member at the University of Gondar, Ethiopia, involved in teaching, research and community service activities. Berihun’s research interest is on life course and perinatal epidemiology, developmental origins of health and disease, child and adolescent mental health and maternal and child health. His current research focuses on the impact of early life adversities on mental health and neurodevelopmental disorders in offspring.

Presenter of 2 Presentations

 Conference Calendar
e-Poster Presentations (ID 1106) AS03. Child and Adolescent Psychiatry

EPP0144 - Maternal perinatal depressive symptoms and oppositional-defiant disorder in children and adolescents

Session Name
e-Poster Presentations (ID 1106)
Date
Sun, 11.04.2021
Session Time
07:30 - 23:59
Room
e-Poster Gallery
Lecture Time
07:30 - 07:30
Presenter

ABSTRACT

Introduction

There is evidence that maternal perinatal depression is associated with adverse neurodevelopmental and mental health outcomes in children. No study has yet examined the association between maternal depressive symptoms during pregnancy and the postpartum period and the risk of oppositional-defiant disorder (ODD) in children and adolescents.

Objectives

This study aimed to investigate whether there is an association between perinatal depressive symptoms and the risk of ODD in offspring from age 7 to 15 years.

Methods

We used data from the Avon Longitudinal Study of Parents and Children (ALSPAC), a population-based prospective birth cohort study in the UK. Offspring ODD at the age of 7, 10, 13 and 15 years were assessed by using parental reports the Development and Well-Being Assessment (DAWBA). We applied Generalized Estimating Equation (GEE) modelling to examine associations across the four time points.

Results

Maternal postnatal depressive symptoms were associated with more a two-fold increased risk of ODD overall. Third trimester depressive symptoms (measured at 32 weeks of gestation) increased risk of ODD by 72%. Offspring of mothers who had depressive symptoms both during pregnancy and in the first year of postpartum period have a four-fold increased risk of ODD over time (adjusted OR = 3.59 (1.98-6.52).

Conclusions

Offspring of mothers with perinatal depressive symptoms are at an increased risk of developing behavioural disorders.

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Oral Communications (ID 1110) AS49. Women, Gender and Mental Health

O322 - The impact of hypertensive disorders during pregnancy on maternal perinatal depressive and anxiety symptoms

Session Name
Oral Communications (ID 1110)
Date
Sat, 10.04.2021
Session Time
07:00 - 21:00
Room
On Demand
Lecture Time
08:56 - 09:08
Presenter

ABSTRACT

Introduction

Existing evidence regarding the association between hypertensive disorders of pregnancy (HDP) and the risk of maternal mental illness is inconclusive.

Objectives

This study aimed (i) to investigate the relationship between HDP (pre-eclampsia and gestational hypertension) and the risk of depressive and anxiety symptoms during pregnancy and in the postpartum period and (ii) to test whether parity moderates the association between HDP and antenatal and postnatal anxiety and depressive symptoms.

Methods

The study cohort consisted of more than 8500 mothers who participated in the Avon Longitudinal Study of Parents and Children (ALSPAC), UK. Maternal antenatal and postnatal depressive and anxiety symptoms were assessed using the Edinburgh Postnatal Depression Scale (EPDS) and the Crown-Crisp Experiential Index (CCEI), respectively. Univariable and multivariable logistic and linear regression analyses were used to examine the associations.

Results

Mothers with pre-eclampsia had a 53% (aOR= 1.53; 95% CI, 1.06-2.23) increased risk of antenatal depressive symptoms compared with those without pre-eclampsia. Having pre-eclampsia and being a nulliparous woman resulted in a 2.75 fold increased risk of antenatal depressive symptoms (p-value for interaction = 0.03). Gestational hypertension was associated with antenatal depressive and anxiety symptoms. We found no associations between pre-eclampsia and/or gestational hypertension and postnatal anxiety and depressive symptoms.

Conclusions

Our study showed that mothers with HDP were at higher risk of antenatal depressive and anxiety symptoms. Nulliparous women with pre-eclampsia are a higher risk group for depression during pregnancy.

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